ENSGALG00000017350


Gallus gallus

Features
Gene ID: ENSGALG00000017350
  
Biological name :RRM1
  
Synonyms : ribonucleoside-diphosphate reductase large subunit / RRM1
  
Possible biological names infered from orthology : P07742 / P23921 / ribonucleotide reductase catalytic subunit M1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 194676693
Gene end: 194694707
  
Corresponding Affymetrix probe sets: Gga.4514.2.S1_s_at (Chicken Array)   Gga.4514.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027981
Ensembl peptide - ENSGALP00000062501
NCBI entrez gene - 419081     See in Manteia.
RefSeq - NM_001030837
RefSeq Peptide - NP_001026008
swissprot - E1C4Q0
swissprot - A0A1L1RUK4
Ensembl - ENSGALG00000017350
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rrm1ENSDARG00000014017Danio rerio
 RRM1ENSG00000167325Homo sapiens
 Rrm1ENSMUSG00000030978Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000788  Ribonucleotide reductase large subunit, C-terminal
 IPR005144  ATP-cone domain
 IPR008926  Ribonucleotide reductase R1 subunit, N-terminal
 IPR013346  Ribonucleotide reductase, class I , alpha subunit
 IPR013509  Ribonucleotide reductase large subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0009263 deoxyribonucleotide biosynthetic process IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0051290 protein heterotetramerization IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005971 ribonucleoside-diphosphate reductase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0017076 purine nucleotide binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017350 RRM1 / ribonucleoside-diphosphate reductase large subunit / P07742* / P23921* / ribonucleotide reductase catalytic subunit M1*  / complex
 ENSGALG00000015704 TXN / P08629 / Thioredoxin / Txn1* / TXNDC2* / P10599* / P10639* / Q86VQ3* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 2 (spermatozoa)*  / reaction
 ENSGALG00000016442 RRM2* / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *  / complex
 ENSGALG00000040921 RRM2B / ribonucleotide reductase regulatory TP53 inducible subunit M2B / Q6PEE3* / Q7LG56* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rrm2b), transcript variant 3, mRNA.*  / complex






 

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