ENSDARG00000014017


Danio rerio

Features
Gene ID: ENSDARG00000014017
  
Biological name :rrm1
  
Synonyms : ribonucleotide reductase M1 polypeptide / rrm1
  
Possible biological names infered from orthology : P07742 / P23921 / Ribonucleoside-diphosphate reductase large subunit / ribonucleotide reductase catalytic subunit M1
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 30772043
Gene end: 30787414
  
Corresponding Affymetrix probe sets: Dr.9746.1.S1_a_at (Zebrafish Array)   NM_131455_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000010800
NCBI entrez gene - 30740     See in Manteia.
RefSeq - NM_131455
RefSeq Peptide - NP_571530
swissprot - F1R2K9
ZFIN ID - ZDB-GENE-990415-247
Ensembl - ENSDARG00000014017
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RRM1ENSGALG00000017350Gallus gallus
 RRM1ENSG00000167325Homo sapiens
 Rrm1ENSMUSG00000030978Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000788  Ribonucleotide reductase large subunit, C-terminal
 IPR005144  ATP-cone domain
 IPR008926  Ribonucleotide reductase R1 subunit, N-terminal
 IPR013346  Ribonucleotide reductase, class I , alpha subunit
 IPR013509  Ribonucleotide reductase large subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism sigmoid , abnormal
Show

 ZFA:0001114 head head shape , abnormal
head decreased width , abnormal
head pointed , abnormal
Show

 ZFA:0001115 trunk trunk sigmoid , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033367 rrm2b / ribonucleotide reductase M2 b / Q7LG56* / Q6PEE3* / ribonucleotide reductase regulatory TP53 inducible subunit M2B* / Mus musculus ribonucleotide reductase M2 B (TP53 inducible) (Rr...  / complex
 ENSDARG00000014017 rrm1 / ribonucleotide reductase M1 polypeptide / P07742* / P23921* / ribonucleotide reductase catalytic subunit M1* / Ribonucleoside-diphosphate reductase large subunit *  / complex
 ENSDARG00000031435 zgc:56493 / TXN* / Txn1* / Q6A555* / Q86VQ3* / P10639* / Q69AB2* / TXNDC2* / TXNDC8* / P10599* / thioredoxin* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain contai...  / reaction
 ENSDARG00000044125 txn / thioredoxin / Txn1* / Q6A555* / Q86VQ3* / TXNDC8* / P10599* / P10639* / Q69AB2* / TXNDC2* / thioredoxin 1* / thioredoxin domain containing 2* / thioredoxin domain containing 8* / thio...  / reaction
 ENSDARG00000020711 rrm2 / P79733 / ribonucleotide reductase M2 polypeptide / P31350* / P11157* / AC007240.1* / ribonucleotide reductase regulatory subunit M2* / Ribonucleoside-diphosphate reductase subunit M2 *  / complex






 

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