ENSDARG00000078217


Danio rerio

Features
Gene ID: ENSDARG00000078217
  
Biological name :cblc
  
Synonyms : cblc / Cbl proto-oncogene C, E3 ubiquitin protein ligase
  
Possible biological names infered from orthology : Cbl proto-oncogene C / E3 ubiquitin-protein ligase CBL-C / Q80XL1 / Q9ULV8
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 25761101
Gene end: 25800819
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000099237
NCBI entrez gene - 565383     See in Manteia.
RefSeq - NM_001128252
RefSeq Peptide - NP_001121724
swissprot - F6PCP5
ZFIN ID - ZDB-GENE-080220-20
Ensembl - ENSDARG00000078217
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CBLCENSG00000142273Homo sapiens
 CblcENSMUSG00000040525Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cblb / alcama / Cbl proto-oncogene B, E3 ubiquitin protein ligase / Q3TTA7* / Q13191* / Cbl proto-oncogene B* / E3 ubiquitin-protein ligase CBL-B *ENSDARG0000001519953
cbl / Cbl proto-oncogene, E3 ubiquitin protein ligase / P22682* / P22681* / Cbl proto-oncogene* / E3 ubiquitin-protein ligase CBL *ENSDARG0000000995853


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001841  Zinc finger, RING-type
 IPR003153  Adaptor protein Cbl, N-terminal helical
 IPR011992  EF-hand domain pair
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014741  Adaptor protein Cbl, EF hand-like
 IPR014742  Adaptor protein Cbl, SH2-like domain
 IPR024159  Adaptor protein Cbl, PTB domain
 IPR024162  Adaptor protein Cbl


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IBA
 biological_processGO:0007175 negative regulation of epidermal growth factor-activated receptor activity IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0023051 regulation of signaling IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0045121 membrane raft IBA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0017124 SH3 domain binding IBA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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