ENSDARG00000078654


Danio rerio

Features
Gene ID: ENSDARG00000078654
  
Biological name :tpx2
  
Synonyms : tpx2 / TPX2, microtubule-associated, homolog (Xenopus laevis)
  
Possible biological names infered from orthology : A2APB8 / Q9ULW0 / Targeting protein for Xklp2 / TPX2, microtubule nucleation factor
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 32028574
Gene end: 32039790
  
Corresponding Affymetrix probe sets: Dr.4703.1.S1_at (Zebrafish Array)   Dr.4703.1.S2_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000112519
Ensembl peptide - ENSDARP00000157350
Ensembl peptide - ENSDARP00000119079
Ensembl peptide - ENSDARP00000101360
NCBI entrez gene - 107966129     See in Manteia.
RefSeq - XM_017353499
RefSeq - XM_017353500
RefSeq - NM_001327745
RefSeq Peptide - NP_001314674
swissprot - E9QE51
swissprot - E9QBN1
swissprot - F1RB66
ZFIN ID - ZDB-GENE-030131-9652
Ensembl - ENSDARG00000078654
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TPX2ENSGALG00000006267Gallus gallus
 TPX2ENSG00000088325Homo sapiens
 Tpx2ENSMUSG00000027469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009675  TPX2
 IPR027329  TPX2, C-terminal
 IPR027330  TPX2 central domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0060236 regulation of mitotic spindle organization IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005874 microtubule IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Activity through Phosphorylation
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021794 hmmr / hyaluronan-mediated motility receptor (RHAMM) / O75330* / Q00547* / hyaluronan mediated motility receptor*  / reaction / complex






 

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contact: otassy@igbmc.fr