ENSGALG00000006267


Gallus gallus

Features
Gene ID: ENSGALG00000006267
  
Biological name :TPX2
  
Synonyms : targeting protein for Xklp2 / TPX2
  
Possible biological names infered from orthology : A2APB8 / Q9ULW0 / TPX2, microtubule nucleation factor
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 10235385
Gene end: 10247594
  
Corresponding Affymetrix probe sets: Gga.5141.1.S1_s_at (Chicken Array)   GgaAffx.12961.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000061056
Ensembl peptide - ENSGALP00000064194
Ensembl peptide - ENSGALP00000010115
NCBI entrez gene - 395081     See in Manteia.
RefSeq - XM_015296325
RefSeq - NM_204437
RefSeq - XM_015296323
RefSeq - XM_015296324
RefSeq Peptide - NP_989768
swissprot - A0A1L1RZ92
swissprot - F1NW64
swissprot - A0A1L1RQH7
Ensembl - ENSGALG00000006267
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpx2ENSDARG00000078654Danio rerio
 TPX2ENSG00000088325Homo sapiens
 Tpx2ENSMUSG00000027469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009675  TPX2
 IPR015128  Aurora-A binding
 IPR027329  TPX2, C-terminal
 IPR027330  TPX2 central domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0060236 regulation of mitotic spindle organization IEA
 biological_processGO:0090307 mitotic spindle assembly IEA
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IEA
 cellular_componentGO:0043203 axon hillock IEA
 cellular_componentGO:0045171 intercellular bridge IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0061676 importin-alpha family protein binding IEA


Pathways (from Reactome)
Pathway description
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000042009 HMMR / hyaluronan mediated motility receptor / O75330* / Q00547*  / reaction / complex
 ENSGALG00000007768 AURKA / aurora kinase A / O14965* / P97477*  / complex / reaction






 

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