ENSDARG00000090183


Danio rerio

Features
Gene ID: ENSDARG00000090183
  
Biological name :gapvd1
  
Synonyms : gapvd1 / GTPase activating protein and VPS9 domains 1
  
Possible biological names infered from orthology : GTPase-activating protein and VPS9 domain-containing protein 1 / Q14C86 / Q6PAR5
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 34341885
Gene end: 34427371
  
Corresponding Affymetrix probe sets: Dr.26138.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000146934
Ensembl peptide - ENSDARP00000153426
Ensembl peptide - ENSDARP00000148180
Ensembl peptide - ENSDARP00000100555
Ensembl peptide - ENSDARP00000102755
Ensembl peptide - ENSDARP00000139737
NCBI entrez gene - 436693     See in Manteia.
RefSeq - NM_001002420
RefSeq - XM_005167157
RefSeq Peptide - NP_001002420
swissprot - E7F237
swissprot - Q6DH32
swissprot - A0A0R4IS53
ZFIN ID - ZDB-GENE-040718-117
Ensembl - ENSDARG00000090183
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GAPVD1ENSGALG00000000993Gallus gallus
 GAPVD1ENSG00000165219Homo sapiens
 Gapvd1ENSMUSG00000026867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rabgef1 / RAB guanine nucleotide exchange factor (GEF) 1 / Q9JM13* / Q9UJ41* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*ENSDARG000000144307
rabgef1l / RAB guanine nucleotide exchange factor (GEF) 1, like / Q9JM13* / Q9UJ41* / RABGEF1* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*ENSDARG000000159686


Protein motifs (from Interpro)
Interpro ID Name
 IPR001936  Ras GTPase-activating domain
 IPR003123  VPS9 domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000056122 gdi1 / GDP dissociation inhibitor 1 / P31150* / P50396* / Rab GDP dissociation inhibitor alpha *  / reaction






 

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