ENSDARG00000014430


Danio rerio

Features
Gene ID: ENSDARG00000014430
  
Biological name :rabgef1
  
Synonyms : rabgef1 / RAB guanine nucleotide exchange factor (GEF) 1
  
Possible biological names infered from orthology : AC027644.4 / Q9JM13 / Q9UJ41 / Rab5 GDP/GTP exchange factor / RAB guanine nucleotide exchange factor 1
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 32854901
Gene end: 32880298
  
Corresponding Affymetrix probe sets: Dr.9342.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000016779
Ensembl peptide - ENSDARP00000112905
Ensembl peptide - ENSDARP00000120214
NCBI entrez gene - 393816     See in Manteia.
RefSeq - NM_200843
RefSeq - XM_005172645
RefSeq - XM_009305366
RefSeq Peptide - NP_957137
swissprot - Q6P6Y4
swissprot - F1QCS5
ZFIN ID - ZDB-GENE-040426-1486
Ensembl - ENSDARG00000014430
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000021611Gallus gallus
 AC027644.4ENSG00000284461Homo sapiens
 Q9UJ41ENSG00000154710Homo sapiens
 Q9JM13ENSMUSG00000025340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rabgef1l / RAB guanine nucleotide exchange factor (GEF) 1, like / Q9JM13* / Q9UJ41* / RABGEF1* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*ENSDARG0000001596851
gapvd1 / GTPase activating protein and VPS9 domains 1 / Q14C86* / Q6PAR5* / GTPase-activating protein and VPS9 domain-containing protein 1 *ENSDARG000000901837


Protein motifs (from Interpro)
Interpro ID Name
 IPR002653  Zinc finger, A20-type
 IPR003123  VPS9 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001557 pronephric glomerulus pronephric glomerulus permeability , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000051836 si:dkeyp-19e1.3 / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / A6NDS4* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TBC1...  / reaction / complex
 ENSDARG00000011088 si:ch211-288d18.1 / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / A6NDS4* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TB...  / complex / reaction
 ENSDARG00000026712 rab5c / RAB5C, member RAS oncogene family / P35278* / P51148*  / complex
 ENSDARG00000038537 gga1 / golgi-associated, gamma adaptin ear containing, ARF binding protein 1 / Q8R0H9* / Q9UJY5* / ADP-ribosylation factor-binding protein GGA1 *  / complex
 ENSDARG00000098871 GGA3 (1 of many) / si:ch73-157i16.3 / GGA3* / Q9NZ52* / Q8BMI3* / ADP-ribosylation factor-binding protein GGA3 * / golgi associated, gamma adaptin ear containing, ARF binding protein 3*  / complex






 

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