ENSDARG00000098871


Danio rerio

Features
Gene ID: ENSDARG00000098871
  
Biological name :GGA3 (1 of many)
  
Synonyms : GGA3 (1 of many) / si:ch73-157i16.3
  
Possible biological names infered from orthology : ADP-ribosylation factor-binding protein GGA3 / GGA3 / golgi associated, gamma adaptin ear containing, ARF binding protein 3 / Q8BMI3 / Q9NZ52
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 6490520
Gene end: 6519760
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000133201
Ensembl peptide - ENSDARP00000138374
Ensembl peptide - ENSDARP00000147589
NCBI entrez gene - 100334661     See in Manteia.
swissprot - A0A0R4IFN1
swissprot - A0A0R4ISY9
ZFIN ID - ZDB-GENE-131126-18
Ensembl - ENSDARG00000098871
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GGA3ENSGALG00000007992Gallus gallus
 GGA3ENSG00000125447Homo sapiens
 Gga3ENSMUSG00000020740Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gga3 / ggolgi-associated, gamma adaptin ear containing, ARF binding protein 3 / Q8BMI3* / Q9NZ52* / ADP-ribosylation factor-binding protein GGA3 * / golgi associated, gamma adaptin ear cont...ENSDARG0000010366752
gga1 / golgi-associated, gamma adaptin ear containing, ARF binding protein 1 / Q8R0H9* / Q9UJY5* / ADP-ribosylation factor-binding protein GGA1 *ENSDARG0000003853742
TOM1L2 / Danio rerio target of myb1 like 2 membrane trafficking protein (tom1l2), mRNA. / Q6ZVM7* / target of myb1 like 2 membrane trafficking protein*ENSDARG0000005639415
tom1l2 / target of myb1 like 2 membrane trafficking protein / Q5SRX1* / Q6ZVM7* / TOM1-like protein 2 *ENSDARG0000000921715
tom1 / target of myb1 membrane trafficking protein / O60784* / O88746* / target of myb1 trafficking protein*ENSDARG0000010458113


Protein motifs (from Interpro)
Interpro ID Name
 IPR002014  VHS domain
 IPR004152  GAT domain
 IPR008152  Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
 IPR008153  Gamma-adaptin ear (GAE) domain
 IPR008942  ENTH/VHS
 IPR013041  Clathrin adaptor, appendage, Ig-like subdomain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0030131 clathrin adaptor complex IEA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs
MET receptor recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026712 rab5c / RAB5C, member RAS oncogene family / P35278* / P51148*  / complex
 ENSDARG00000028699 crkl / v-crk avian sarcoma virus CT10 oncogene homolog-like / P46109* / P47941* / Crk-like protein * / CRK like proto-oncogene, adaptor protein*  / complex
 ENSDARG00000052928 arf6b / ADP-ribosylation factor 6b / ARF6* / P62330* / P62331* / ADP ribosylation factor 6*  / complex
 ENSDARG00000055635 crk / v-crk avian sarcoma virus CT10 oncogene homolog / P46108* / Q64010* / Adapter molecule crk * / CRK proto-oncogene, adaptor protein*  / complex
 ENSDARG00000037018 gab1 / GRB2-associated binding protein 1 / Q13480* / Q9QYY0*  / complex
 ENSDARG00000045544 hgfa / hepatocyte growth factor a / HGF* / P14210* / Q08048* / hepatocyte growth factor* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / complex
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / complex
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex
 ENSDARG00000051836 si:dkeyp-19e1.3 / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / A6NDS4* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TBC1...  / complex / reaction
 ENSDARG00000011088 si:ch211-288d18.1 / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / A6NDS4* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TB...  / reaction / complex
 ENSDARG00000014430 rabgef1 / RAB guanine nucleotide exchange factor (GEF) 1 / Q9JM13* / Q9UJ41* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*  / complex






 

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