ENSDARG00000052928


Danio rerio

Features
Gene ID: ENSDARG00000052928
  
Biological name :arf6b
  
Synonyms : ADP-ribosylation factor 6b / arf6b
  
Possible biological names infered from orthology : ADP ribosylation factor 6 / ARF6 / P62330 / P62331
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 45731865
Gene end: 45734459
  
Corresponding Affymetrix probe sets: Dr.7023.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000069359
Ensembl peptide - ENSDARP00000119598
Ensembl peptide - ENSDARP00000153097
NCBI entrez gene - 100003206     See in Manteia.
RefSeq - NM_001161375
RefSeq Peptide - NP_001154847
swissprot - Q6P2U5
ZFIN ID - ZDB-GENE-030131-9056
Ensembl - ENSDARG00000052928
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARF6ENSGALG00000026944Gallus gallus
 ARF6ENSG00000165527Homo sapiens
 Arf6ENSMUSG00000044147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
arf6a / ADP-ribosylation factor 6a / ARF6* / P62330* / ADP ribosylation factor 6*ENSDARG00000101626100
arf2a / ADP-ribosylation factor 2aENSDARG0000001476370
arf2b / ADP-ribosylation factor 2b / Arf2* / Q8BSL7* / ADP-ribosylation factor 2 *ENSDARG0000001639369
arf1 / ADP-ribosylation factor 1ENSDARG0000000948469
arf3a / ADP-ribosylation factor 3a / ARF3* / P61204* / P61205* / ADP ribosylation factor 3*ENSDARG0000007053969
arf3b / ADP-ribosylation factor 3bENSDARG0000003699868
zgc:77650 / ARF5* / P84084* / P84085* / ADP ribosylation factor 5*ENSDARG0000011389967
arf5 / ADP-ribosylation factor 5 / P84085*ENSDARG0000007047267
arf4a / ADP-ribosylation factor 4a / ARF5* / P84084* / P84085* / ADP ribosylation factor 5*ENSDARG0000004598967
arf4b / ADP-ribosylation factor 4bENSDARG0000010033963
si:ch1073-165f9.2ENSDARG0000007387658
zgc:110286ENSDARG0000007421057
trim23 / tripartite motif containing 23 / P36406* / Q8BGX0* / E3 ubiquitin-protein ligase TRIM23 *ENSDARG0000006942050
arl3l2 / ADP-ribosylation factor-like 3, like 2ENSDARG0000001540445
arl3 / Q1MTE5 / ADP-ribosylation factor-like 3 / P36405* / Q9WUL7* / ADP ribosylation factor like GTPase 3* / ADP-ribosylation factor-like protein 3 *ENSDARG0000007140945
zgc:110197 / ARL3 (1 of many) / ARL3* / P36405* / Q9WUL7* / ADP ribosylation factor like GTPase 3* / ADP-ribosylation factor-like protein 3 *ENSDARG0000005679445
arl2 / ADP-ribosylation factor-like 2 / Q9D0J4* / P36404* / ARL2-SNX15* / ADP ribosylation factor like GTPase 2* / ARL2-SNX15 readthrough (NMD candidate)* / ADP-ribosylation factor-like protein 2 *ENSDARG0000006949645
arl3l1 / ADP-ribosylation factor-like 3, like 1ENSDARG0000011110644
arl14 / ADP-ribosylation factor-like 14 / Q8N4G2* / ADP ribosylation factor like GTPase 14*ENSDARG0000006322342
arl11 / ADP-ribosylation factor-like 11 / Q6P3A9* / Q969Q4* / ADP ribosylation factor like GTPase 11* / ADP-ribosylation factor-like protein 11 *ENSDARG0000003663738


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035622 intrahepatic bile duct development IGI
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IGI
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder absent , abnormal
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 ZFA:0000123 liver liver decreased size , abnormal
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 ZFA:0000140 pancreas pancreas decreased size , abnormal
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 ZFA:0001076 intestinal bulb intestinal bulb decreased size , abnormal
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 ZFA:0005163 bile canaliculus bile canaliculus decreased length , abnormal
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 ZFA:0005164 bile ductule bile ductule decreased length , abnormal
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 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct decreased amount , abnormal
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 ZFA:0009111 hepatocyte hepatocyte decreased functionality , abnormal
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 ZFA:0009379 intrahepatic bile duct epithelial cell intrahepatic bile duct epithelial cell filopodium decreased mobility , abnormal
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 ZFA:0009397 cholangiocyte cholangiocyte decreased amount , abnormal
cholangiocyte filopodium decreased length , abnormal
cholangiocyte aggregated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000098871 GGA3 (1 of many) / si:ch73-157i16.3 / GGA3* / Q9NZ52* / Q8BMI3* / ADP-ribosylation factor-binding protein GGA3 * / golgi associated, gamma adaptin ear containing, ARF binding protein 3*  / complex
 ENSDARG00000060096 tbc1d10ab / TBC1 domain family, member 10Ab / P58802* / Q9BXI6* / TBC1D10A* / AC004997.1* / TBC1 domain family member 10A*  / complex / reaction
 ENSDARG00000045544 hgfa / hepatocyte growth factor a / HGF* / P14210* / Q08048* / hepatocyte growth factor* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / complex
 ENSDARG00000028699 crkl / v-crk avian sarcoma virus CT10 oncogene homolog-like / P46109* / P47941* / Crk-like protein * / CRK like proto-oncogene, adaptor protein*  / complex
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / complex
 ENSDARG00000055635 crk / v-crk avian sarcoma virus CT10 oncogene homolog / P46108* / Q64010* / Adapter molecule crk * / CRK proto-oncogene, adaptor protein*  / complex
 ENSDARG00000037018 gab1 / GRB2-associated binding protein 1 / Q13480* / Q9QYY0*  / complex
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex






 

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