ENSGALG00000026944


Gallus gallus

Features
Gene ID: ENSGALG00000026944
  
Biological name :ARF6
  
Synonyms : ADP-ribosylation factor 6 / ARF6 / P26990
  
Possible biological names infered from orthology : P62330 / P62331
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 57835096
Gene end: 57835623
  
Corresponding Affymetrix probe sets: Gga.2511.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041604
NCBI entrez gene - 428927     See in Manteia.
RefSeq - NM_001081705
RefSeq Peptide - NP_001075174
swissprot - P26990
swissprot - R4GHQ1
Ensembl - ENSGALG00000026944
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arf6aENSDARG00000101626Danio rerio
 arf6bENSDARG00000052928Danio rerio
 ARF6ENSG00000165527Homo sapiens
 Arf6ENSMUSG00000044147Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARF1 / ADP-ribosylation factor 1 / P84077*ENSGALG0000000539369
ARF4 / ADP ribosylation factor 4 / P18085* / P61750*ENSGALG0000000562267
ARF5 / ADP ribosylation factor 5 / P84084* / P84085*ENSGALG0000004347658
TRIM23 / tripartite motif containing 23 / P36406* / Q8BGX0* / E3 ubiquitin-protein ligase TRIM23 *ENSGALG0000001476552
ARL3 / ADP ribosylation factor like GTPase 3 / P36405* / Q9WUL7* / ADP-ribosylation factor-like protein 3 *ENSGALG0000000804945
ARL11 / ADP ribosylation factor like GTPase 11 / Q6P3A9* / Q969Q4* / ADP-ribosylation factor-like protein 11 *ENSGALG0000002273342
ENSGALG0000000313441
ARL14 / ADP ribosylation factor like GTPase 14 / Q8N4G2*ENSGALG0000004362341
ARL8B / ADP ribosylation factor like GTPase 8B / Q9CQW2* / Q9NVJ2* / ADP-ribosylation factor-like protein 8B *ENSGALG0000000831436
ARL8A / ADP-ribosylation factor-like protein 8A / Q8VEH3* / Q96BM9* / ADP ribosylation factor like GTPase 8A*ENSGALG0000000060634
ARL15 / ADP ribosylation factor like GTPase 15 / Q8BGR6* / Q9NXU5* / ADP-ribosylation factor-like protein 15 *ENSGALG0000001491132
ARL8BLENSGALG0000003152731


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0030866 cortical actin cytoskeleton organization IEA
 biological_processGO:0032456 endocytic recycling IEA
 biological_processGO:0033028 myeloid cell apoptotic process IEA
 biological_processGO:0034394 protein localization to cell surface IEA
 biological_processGO:0035020 regulation of Rac protein signal transduction IEA
 biological_processGO:0036010 protein localization to endosome IEA
 biological_processGO:0051489 regulation of filopodium assembly IEA
 biological_processGO:0060998 regulation of dendritic spine development IEA
 biological_processGO:0090162 establishment of epithelial cell polarity IEA
 biological_processGO:0097178 ruffle assembly IEA
 biological_processGO:0097284 hepatocyte apoptotic process IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 biological_processGO:2000009 negative regulation of protein localization to cell surface IEA
 cellular_componentGO:0001726 ruffle ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 cellular_componentGO:0031527 filopodium membrane IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 cellular_componentGO:0090543 Flemming body IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0031996 thioesterase binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs
Clathrin-mediated endocytosis
MET receptor recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002656 CRK / Q04929 / Adapter molecule crk / P46108* / Q64010* / CRK proto-oncogene, adaptor protein*  / complex
 ENSGALG00000007954 P58802* / Q9BXI6* / TBC1D10A* / AC004997.1* / TBC1 domain family member 10A*  / complex / reaction
 ENSGALG00000006390 CRKL / CRK like proto-oncogene, adaptor protein / P46109* / P47941* / Crk-like protein *  / complex
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / complex
 ENSGALG00000009898 GAB1 / GRB2 associated binding protein 1 / Q13480* / Q9QYY0*  / complex
 ENSGALG00000036883 MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*  / complex
 ENSGALG00000033974 HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr