ENSGALG00000005622


Gallus gallus

Features
Gene ID: ENSGALG00000005622
  
Biological name :ARF4
  
Synonyms : ADP ribosylation factor 4 / ARF4
  
Possible biological names infered from orthology : P18085 / P61750
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 8722023
Gene end: 8732436
  
Corresponding Affymetrix probe sets: Gga.6997.1.S1_s_at (Chicken Array)   Gga.6997.2.A1_at (Chicken Array)   Gga.6997.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009007
Ensembl peptide - ENSGALP00000044203
NCBI entrez gene - 769725     See in Manteia.
RefSeq - XM_015293388
swissprot - A0A1D5NV30
swissprot - F1NGS7
Ensembl - ENSGALG00000005622
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARF4ENSG00000168374Homo sapiens
 Arf4ENSMUSG00000021877Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARF1 / ADP-ribosylation factor 1 / P84077*ENSGALG0000000539380
ARF5 / ADP ribosylation factor 5 / P84084* / P84085*ENSGALG0000004347677
ARF6 / P26990 / ADP-ribosylation factor 6 / P62330* / P62331*ENSGALG0000002694463
TRIM23 / tripartite motif containing 23 / P36406* / Q8BGX0* / E3 ubiquitin-protein ligase TRIM23 *ENSGALG0000001476556
ARL3 / ADP ribosylation factor like GTPase 3 / P36405* / Q9WUL7* / ADP-ribosylation factor-like protein 3 *ENSGALG0000000804942
ARL14 / ADP ribosylation factor like GTPase 14 / Q8N4G2*ENSGALG0000004362341
ARL11 / ADP ribosylation factor like GTPase 11 / Q6P3A9* / Q969Q4* / ADP-ribosylation factor-like protein 11 *ENSGALG0000002273339
ENSGALG0000000313438
ARL8B / ADP ribosylation factor like GTPase 8B / Q9CQW2* / Q9NVJ2* / ADP-ribosylation factor-like protein 8B *ENSGALG0000000831431
ARL15 / ADP ribosylation factor like GTPase 15 / Q8BGR6* / Q9NXU5* / ADP-ribosylation factor-like protein 15 *ENSGALG0000001491130
ARL8A / ADP-ribosylation factor-like protein 8A / Q8VEH3* / Q96BM9* / ADP ribosylation factor like GTPase 8A*ENSGALG0000000060629
ARL8BLENSGALG0000003152727


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006471 protein ADP-ribosylation IEA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IEA
 biological_processGO:0007612 learning IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0031584 activation of phospholipase D activity IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045176 apical protein localization IEA
 biological_processGO:0045197 establishment or maintenance of epithelial cell apical/basal polarity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060996 dendritic spine development IEA
 biological_processGO:0061512 protein localization to cilium IEA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0043197 dendritic spine IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
VxPx cargo-targeting to cilium
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003153 COPE / Q5ZIK9 / Coatomer subunit epsilon / O14579* / O89079* / coatomer protein complex subunit epsilon*  / complex / reaction
 ENSGALG00000005357 COPB2 / coatomer protein complex subunit beta 2 / O55029* / P35606* / Coatomer subunit beta *  / complex / reaction
 ENSGALG00000007615 Q5ZJN2 / RAB11A / Ras-related protein Rab-11A / P62491* / P62492* / RAB11A, member RAS oncogene family*  / complex
 ENSGALG00000005714 PKD1 / polycystin 1, transient receptor potential channel interacting / O08852* / P98161* / Polycystin-1 *  / complex / reaction
 ENSGALG00000006015 COPB1 / Q5ZIA5 / Coatomer subunit beta / P53618* / Q9JIF7* / coatomer protein complex subunit beta 1*  / complex / reaction
 ENSGALG00000007430 ARCN1 / Q5ZL57 / Coatomer subunit delta / P48444* / Q5XJY5* / archain 1*  / complex / reaction
 ENSGALG00000037618 ASAP1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 / Q9QWY8* / Q9ULH1* / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 *  / complex






 

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