ENSGALG00000037618


Gallus gallus

Features
Gene ID: ENSGALG00000037618
  
Biological name :ASAP1
  
Synonyms : ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 / ASAP1
  
Possible biological names infered from orthology : Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 / Q9QWY8 / Q9ULH1
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 140681764
Gene end: 140794785
  
Corresponding Affymetrix probe sets: Gga.12707.1.S1_s_at (Chicken Array)   Gga.14179.1.S1_at (Chicken Array)   GgaAffx.21048.1.S1_s_at (Chicken Array)   GgaAffx.24927.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049537
Ensembl peptide - ENSGALP00000053907
NCBI entrez gene - 428385     See in Manteia.
RefSeq - XM_015283133
RefSeq - XM_015283134
RefSeq - XM_015283135
RefSeq - XM_425945
swissprot - A0A1D5PM34
swissprot - A0A1D5P9X9
Ensembl - ENSGALG00000037618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asap1aENSDARG00000029463Danio rerio
 asap1bENSDARG00000039729Danio rerio
 ASAP1ENSG00000153317Homo sapiens
 Asap1ENSMUSG00000022377Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASAP2 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 / O43150* / Q7SIG6* / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 *ENSGALG0000001641955
ENSGALG0000003408536
ASAP3 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 / Q5U464* / Q8TDY4* / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 *ENSGALG0000003694931
ACAP2 / Q5ZK62 / Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 / Q15057* / Q6ZQK5* / ArfGAP with coiled-coil, ankyrin repeat and PH domains 2*ENSGALG0000000704016
AGAP1* / AGAP4* / AGAP5* / AGAP6* / AGAP9* / A6NIR3* / Q5VTM2* / Q5VW22* / Q8BXK8* / Q96P64* / Q9UPQ3* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 1* / ArfGAP with GTPase doma...ENSGALG0000000404514
ACAP3 / ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 / Q96P50*ENSGALG0000003329313
AGAP3* / Q96P47* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3* / arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform b *ENSGALG000000435768
AGAP3* / Q96P47* / ArfGAP with GTPase domain, ankyrin repeat and PH domain 3* / arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform b *ENSGALG000000312763
ENSGALG000000017702


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR002110  Ankyrin repeat
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:0061000 negative regulation of dendritic spine development IEA
 biological_processGO:0071803 positive regulation of podosome assembly IEA
 biological_processGO:1903527 positive regulation of membrane tubulation IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0031253 cell projection membrane IEA
 cellular_componentGO:0043197 dendritic spine IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
VxPx cargo-targeting to cilium


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009959 Q68EF0* / Q96QF0* / RAB3IP* / AC025263.2* / RAB3A interacting protein*  / reaction / complex
 ENSGALG00000028851 RAB8A / Q5F470 / Ras-related protein Rab-8A / P61006* / P55258* / RAB8A, member RAS oncogene family*  / complex / reaction
 ENSGALG00000037618 ASAP1 / ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 / Q9QWY8* / Q9ULH1* / Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 *  / complex
 ENSGALG00000007615 Q5ZJN2 / RAB11A / Ras-related protein Rab-11A / P62491* / P62492* / RAB11A, member RAS oncogene family*  / complex
 ENSGALG00000005714 PKD1 / polycystin 1, transient receptor potential channel interacting / O08852* / P98161* / Polycystin-1 *  / complex
 ENSGALG00000005622 ARF4 / ADP ribosylation factor 4 / P18085* / P61750*  / complex






 

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