Manteia

ENSDARG00000071409

Danio rerio

Features

Gene ID:	ENSDARG00000071409

Biological name :	arl3

Synonyms :	ADP-ribosylation factor-like 3 / arl3 / Q1MTE5

Possible biological names infered from orthology :	ADP ribosylation factor like GTPase 3 / ADP-ribosylation factor-like protein 3 / P36405 / Q9WUL7

Species:	Danio rerio

Chr. number:	12
Strand:	-1
Band:
Gene start:	33966414
Gene end:	33972798

Corresponding Affymetrix probe sets:	Dr.18095.1.S1_at (Zebrafish Array) NM_001044908_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000096322 NCBI entrez gene - 797451 See in Manteia. RefSeq - NM_001044908 RefSeq Peptide - NP_001038373 swissprot - B2GR26 swissprot - Q1MTE5 ZFIN ID - ZDB-GENE-030131-7518 Ensembl - ENSDARG00000071409

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ARL3	ENSGALG00000008049	Gallus gallus
ARL3	ENSG00000138175	Homo sapiens
Arl3	ENSMUSG00000025035	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
zgc:110197 / ARL3 (1 of many) / ARL3* / P36405* / Q9WUL7* / ADP ribosylation factor like GTPase 3* / ADP-ribosylation factor-like protein 3 *	ENSDARG00000056794	95
arl3l2 / ADP-ribosylation factor-like 3, like 2	ENSDARG00000015404	76
arl3l1 / ADP-ribosylation factor-like 3, like 1	ENSDARG00000111106	75
arl2 / ADP-ribosylation factor-like 2 / Q9D0J4* / P36404* / ARL2-SNX15* / ADP ribosylation factor like GTPase 2* / ARL2-SNX15 readthrough (NMD candidate)* / ADP-ribosylation factor-like protein 2 *	ENSDARG00000069496	51
arf2b / ADP-ribosylation factor 2b / Arf2* / Q8BSL7* / ADP-ribosylation factor 2 *	ENSDARG00000016393	45
arf3b / ADP-ribosylation factor 3b	ENSDARG00000036998	45
arf2a / ADP-ribosylation factor 2a	ENSDARG00000014763	45
arf3a / ADP-ribosylation factor 3a / ARF3* / P61204* / P61205* / ADP ribosylation factor 3*	ENSDARG00000070539	44
arf1 / ADP-ribosylation factor 1	ENSDARG00000009484	44
arf6a / ADP-ribosylation factor 6a / ARF6* / P62330* / ADP ribosylation factor 6*	ENSDARG00000101626	43
zgc:77650 / ARF5* / P84084* / P84085* / ADP ribosylation factor 5*	ENSDARG00000113899	43
arf6b / ADP-ribosylation factor 6b / ARF6* / P62330* / P62331* / ADP ribosylation factor 6*	ENSDARG00000052928	43
arf4a / ADP-ribosylation factor 4a / ARF5* / P84084* / P84085* / ADP ribosylation factor 5*	ENSDARG00000045989	43
arl14 / ADP-ribosylation factor-like 14 / Q8N4G2* / ADP ribosylation factor like GTPase 14*	ENSDARG00000063223	43
arf5 / ADP-ribosylation factor 5 / P84085*	ENSDARG00000070472	43
arf4b / ADP-ribosylation factor 4b	ENSDARG00000100339	41
si:ch1073-165f9.2	ENSDARG00000073876	40
trim23 / tripartite motif containing 23 / P36406* / Q8BGX0* / E3 ubiquitin-protein ligase TRIM23 *	ENSDARG00000069420	39
zgc:110286	ENSDARG00000074210	36
arl11 / ADP-ribosylation factor-like 11 / Q6P3A9* / Q969Q4* / ADP ribosylation factor like GTPase 11* / ADP-ribosylation factor-like protein 11 *	ENSDARG00000036637	36

Protein motifs (from Interpro)

Interpro ID	Name
IPR005225	Small GTP-binding protein domain
IPR006689	Small GTPase superfamily, ARF/SAR type
IPR024156	Small GTPase superfamily, ARF type
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000281	mitotic cytokinesis	ISS
biological_process	GO:0007049	cell cycle	IEA
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0051301	cell division	IEA
biological_process	GO:0060271	cilium assembly	IMP
cellular_component	GO:0000139	Golgi membrane	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005634	nucleus	ISS
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005794	Golgi apparatus	ISS
cellular_component	GO:0005813	centrosome	ISS
cellular_component	GO:0005815	microtubule organizing center	IEA
cellular_component	GO:0005819	spindle	IEA
cellular_component	GO:0005856	cytoskeleton	IEA
cellular_component	GO:0005876	spindle microtubule	ISS
cellular_component	GO:0005881	cytoplasmic microtubule	ISS
cellular_component	GO:0005929	cilium	ISS
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030496	midbody	ISS
cellular_component	GO:0032391	photoreceptor connecting cilium	ISS
cellular_component	GO:0042995	cell projection	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	ISS
molecular_function	GO:0005525	GTP binding	ISS
molecular_function	GO:0008017	microtubule binding	ISS
molecular_function	GO:0019003	GDP binding	ISS

Pathways (from Reactome)

Pathway description

Trafficking of myristoylated proteins to the cilium

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000009629	Q90Z08 / unc119.1 / unc-119 homolog 1 / A6NIH7* / Q8C4B4* / UNC119B* / unc-119 lipid binding chaperone B*	/ complex / reaction
ENSDARG00000078261	nphp3 / P0CI65 / nephronophthisis 3 / Q7Z494* / Q7TNH6* / Gm28305* / NPHP3-ACAD11* / nephrocystin 3* / NPHP3-ACAD11 readthrough (NMD candidate)*	/ reaction / complex
ENSDARG00000044339	rp2 / F1QC45 / RP2, ARL3 GTPase activating protein / O75695* / Q9EPK2* / Protein XRP2 *	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr