ENSDARG00000051836


Danio rerio

Features
Gene ID: ENSDARG00000051836
  
Biological name :si:dkeyp-19e1.3
  
Synonyms : si:dkeyp-19e1.3
  
Possible biological names infered from orthology : A0A087WVF3 / A0A087WXS9 / A0A087X179 / A0A087X1G2 / A6NDS4 / B9A6J9 / P0C7X1 / Q2M2D7 / Q6DHY5 / Q6IPX1 / Q86UD7 / Q8IZP1 / TBC1D26 / TBC1D28 / TBC1D3 / TBC1D3B / TBC1D3C / TBC1D3D / TBC1D3E / TBC1D3F / TBC1D3G / TBC1D3H / TBC1D3I / TBC1D3K / TBC1D3L / TBC1 domain family member 26 / TBC1 domain family member 28 / TBC1 domain family member 3 / TBC1 domain family member 3B / TBC1 domain family member 3C / TBC1 domain family member 3D / TBC1 domain family member 3E / TBC1 domain family member 3F / TBC1 domain family member 3G / TBC1 domain family member 3H / TBC1 domain family member 3I / TBC1 domain family member 3K / TBC1 domain family member 3L
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 24121611
Gene end: 24179999
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000118665
NCBI entrez gene - 553000     See in Manteia.
swissprot - F1R1B6
ZFIN ID - ZDB-GENE-081104-56
Ensembl - ENSDARG00000051836
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039221Gallus gallus
 A6NDS4ENSG00000274808Homo sapiens
 B9A6J9ENSG00000274512Homo sapiens
 P0C7X1ENSG00000274226Homo sapiens
 Q2M2D7ENSG00000189375Homo sapiens
 Q6DHY5ENSG00000260287Homo sapiens
 Q6IPX1ENSG00000278299Homo sapiens
 Q86UD7ENSG00000214946Homo sapiens
 Q8IZP1ENSG00000274611Homo sapiens
 TBC1D3DENSG00000274419Homo sapiens
 TBC1D3EENSG00000278599Homo sapiens
 TBC1D3FENSG00000275954Homo sapiens
 TBC1D3IENSG00000274933Homo sapiens
 TBC1D3KENSG00000273513Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch211-288d18.1 / B9A6J9* / TBC1D3* / P0C7X1* / Q2M2D7* / Q6DHY5* / Q6IPX1* / Q8IZP1* / Q86UD7* / A6NDS4* / TBC1D3H* / TBC1D3G* / TBC1D3I* / TBC1D3K* / TBC1D3L* / TBC1D26* / TBC1D28* / TB...ENSDARG0000001108847
usp6nl / USP6 N-terminal like / Q80XC3* / Q92738*ENSDARG0000002218737
tbc1d10b / TBC1 domain family, member 10b / Q4KMP7* / Q8BHL3*ENSDARG0000007860416
tbc1d10ab / TBC1 domain family, member 10Ab / P58802* / Q9BXI6* / TBC1D10A* / AC004997.1* / TBC1 domain family member 10A*ENSDARG0000006009614
tbc1d10c / TBC1 domain family, member 10C / Q8C9V1* / Q8IV04* / Carabin *ENSDARG0000003740814
tbc1d10aa / TBC1 domain family, member 10Aa / P58802* / Q9BXI6* / TBC1D10A* / AC004997.1* / TBC1 domain family member 10A*ENSDARG0000010207013
si:ch211-266k8.4ENSDARG0000008684013
grtp1a / growth hormone regulated TBC protein 1a / GRTP1* / Q5TC63* / growth hormone regulated TBC protein 1*ENSDARG0000002993610
grtp1b / growth hormone regulated TBC protein 1b / GRTP1* / Q5TC63* / Q9D3N8* / growth hormone regulated TBC protein 1*ENSDARG000000302699


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0012505 endomembrane system IBA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014430 rabgef1 / RAB guanine nucleotide exchange factor (GEF) 1 / Q9JM13* / Q9UJ41* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*  / complex / reaction
 ENSDARG00000026712 rab5c / RAB5C, member RAS oncogene family / P35278* / P51148*  / reaction / complex
 ENSDARG00000038537 gga1 / golgi-associated, gamma adaptin ear containing, ARF binding protein 1 / Q8R0H9* / Q9UJY5* / ADP-ribosylation factor-binding protein GGA1 *  / complex / reaction
 ENSDARG00000098871 GGA3 (1 of many) / si:ch73-157i16.3 / GGA3* / Q9NZ52* / Q8BMI3* / ADP-ribosylation factor-binding protein GGA3 * / golgi associated, gamma adaptin ear containing, ARF binding protein 3*  / reaction / complex






 

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