ENSGALG00000000993


Gallus gallus

Features
Gene ID: ENSGALG00000000993
  
Biological name :GAPVD1
  
Synonyms : GAPVD1 / GTPase activating protein and VPS9 domains 1
  
Possible biological names infered from orthology : GTPase-activating protein and VPS9 domain-containing protein 1 / Q14C86 / Q6PAR5
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 10083833
Gene end: 10113057
  
Corresponding Affymetrix probe sets: Gga.10309.1.S1_s_at (Chicken Array)   Gga.10309.2.A1_at (Chicken Array)   Gga.10309.2.S1_s_at (Chicken Array)   Gga.16684.1.S1_at (Chicken Array)   Gga.19056.1.S1_at (Chicken Array)   GgaAffx.22778.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048654
Ensembl peptide - ENSGALP00000052370
Ensembl peptide - ENSGALP00000001464
NCBI entrez gene - 417095     See in Manteia.
RefSeq - XM_015279408
RefSeq - XM_015279405
RefSeq - XM_015279406
RefSeq - XM_015279407
RefSeq - NM_001282210
RefSeq - XM_015279395
RefSeq - XM_015279397
RefSeq - XM_015279398
RefSeq - XM_015279399
RefSeq - XM_015279400
RefSeq - XM_015279401
RefSeq - XM_015279403
RefSeq - XM_015279404
RefSeq Peptide - NP_001269139
swissprot - E1C268
swissprot - A0A1D5PHT9
Ensembl - ENSGALG00000000993
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gapvd1ENSDARG00000090183Danio rerio
 GAPVD1ENSG00000165219Homo sapiens
 Gapvd1ENSMUSG00000026867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9JM13* / Q9UJ41* / RABGEF1* / AC027644.4* / Rab5 GDP/GTP exchange factor * / RAB guanine nucleotide exchange factor 1*ENSGALG000000216117


Protein motifs (from Interpro)
Interpro ID Name
 IPR001936  Ras GTPase-activating domain
 IPR003123  VPS9 domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0051223 regulation of protein transport IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0032794 GTPase activating protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000011272 RAB5A / RAB5A, member RAS oncogene family / P20339* / Q9CQD1* / Ras-related protein Rab-5A *  / complex
 ENSGALG00000022874 RAB31 / RAB31, member RAS oncogene family / Q13636*  / reaction






 

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contact: otassy@igbmc.fr