ENSDARG00000090697


Danio rerio

Features
Gene ID: ENSDARG00000090697
  
Biological name :eif3ea
  
Synonyms : eif3ea / eukaryotic translation initiation factor 3, subunit E, a / Q6DRI1
  
Possible biological names infered from orthology : EIF3E / eukaryotic translation initiation factor 3 subunit E / P60228 / P60229
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 38556836
Gene end: 38631969
  
Corresponding Affymetrix probe sets: Dr.20085.1.S1_at (Zebrafish Array)   NM_200839_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000106853
Ensembl peptide - ENSDARP00000113319
Ensembl peptide - ENSDARP00000116351
NCBI entrez gene - 325102     See in Manteia.
RefSeq - NM_200839
RefSeq Peptide - NP_957133
swissprot - F1R279
swissprot - E9QG06
swissprot - Q6DRI1
ZFIN ID - ZDB-GENE-030131-3827
Ensembl - ENSDARG00000090697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EIF3EENSGALG00000037067Gallus gallus
 EIF3EENSG00000104408Homo sapiens
 Eif3eENSMUSG00000022336Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eif3eb / eukaryotic translation initiation factor 3, subunit E, b / EIF3E* / P60229* / P60228* / eukaryotic translation initiation factor 3 subunit E*ENSDARG0000000254982


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR016650  Eukaryotic translation initiation factor 3 subunit E
 IPR019010  Eukaryotic translation initiation factor 3 subunit E, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IBA
 molecular_functionGO:0003743 translation initiation factor activity IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk grey , abnormal
yolk swollen , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
Show

 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk necrotic , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage malformed , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch aplastic , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage malformed , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage aplastic , abnormal
Show

 ZFA:0009091 melanocyte melanocyte mislocalised , abnormal
melanocyte decreased pigmentation , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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