ENSMUSG00000022336


Mus musculus

Features
Gene ID: ENSMUSG00000022336
  
Biological name :Eif3e
  
Synonyms : Eif3e / Eukaryotic translation initiation factor 3 subunit E / P60229
  
Possible biological names infered from orthology : P60228
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: B3.2
Gene start: 43250058
Gene end: 43282719
  
Corresponding Affymetrix probe sets: 10428398 (MoGene1.0st)   1419822_at (Mouse Genome 430 2.0 Array)   1434523_x_at (Mouse Genome 430 2.0 Array)   1439268_x_at (Mouse Genome 430 2.0 Array)   1460432_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022960
NCBI entrez gene - 16341     See in Manteia.
MGI - MGI:99257
RefSeq - NM_008388
RefSeq Peptide - NP_032414
swissprot - P60229
swissprot - Q3UIG0
Ensembl - ENSMUSG00000022336
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3eaENSDARG00000090697Danio rerio
 eif3ebENSDARG00000002549Danio rerio
 EIF3EENSGALG00000037067Gallus gallus
 EIF3EENSG00000104408Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR016650  Eukaryotic translation initiation factor 3 subunit E
 IPR019010  Eukaryotic translation initiation factor 3 subunit E, N-terminal
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation ISO
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:1902416 positive regulation of mRNA binding IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 cellular_componentGO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e IEA
 molecular_functionGO:0003743 translation initiation factor activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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