ENSDARG00000091459


Danio rerio

Features
Gene ID: ENSDARG00000091459
  
Biological name :gabra2a
  
Synonyms : gabra2a / gamma-aminobutyric acid type A receptor alpha2 subunit a
  
Possible biological names infered from orthology : GABRA2 / Gamma-aminobutyric acid receptor subunit alpha-2 / gamma-aminobutyric acid type A receptor alpha2 subunit / P26048 / P47869
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 12120664
Gene end: 12151350
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000073899
Ensembl peptide - ENSDARP00000110973
NCBI entrez gene - 100150704     See in Manteia.
swissprot - E7F635
swissprot - E7F6S8
ZFIN ID - ZDB-GENE-141216-16
Ensembl - ENSDARG00000091459
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GABRA2ENSGALG00000014206Gallus gallus
 GABRA2ENSG00000151834Homo sapiens
 Gabra2ENSMUSG00000000560Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gabra1 / gamma-aminobutyric acid (GABA) A receptor, alpha 1 / P14867* / P62812* / gamma-aminobutyric acid type A receptor alpha1 subunit* / Mus musculus gamma-aminobutyric acid (GABA) A rec...ENSDARG0000006898976
gabra5 / gamma-aminobutyric acid (GABA) A receptor, alpha 5 / P31644* / Q8BHJ7* / Gamma-aminobutyric acid receptor subunit alpha-5 * / gamma-aminobutyric acid type A receptor alpha5 subunit*ENSDARG0000007073067
gabra4 / gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 / P48169* / gamma-aminobutyric acid type A receptor alpha4 subunit*ENSDARG0000001338958
gabra6b / gamma-aminobutyric acid (GABA) A receptor, alpha 6b / GABRA6* / Q16445* / gamma-aminobutyric acid type A receptor alpha6 subunit*ENSDARG0000005873655
gabra6a / gamma-aminobutyric acid (GABA) A receptor, alpha 6a / Q16445* / GABRA6* / P16305* / Gamma-aminobutyric acid receptor subunit alpha-6 * / gamma-aminobutyric acid type A receptor al...ENSDARG0000007505850
gabra3 / gamma-aminobutyric acid (GABA) A receptor, alpha 3 / P34903* / gamma-aminobutyric acid type A receptor alpha3 subunit*ENSDARG0000009088348
gabrg2 / gamma-aminobutyric acid (GABA) A receptor, gamma 2 / P18507* / P22723* / Gamma-aminobutyric acid receptor subunit gamma-2 * / gamma-aminobutyric acid type A receptor gamma2 subunit*ENSDARG0000005366542
gabrg1 / gamma-aminobutyric acid type A receptor gamma1 subunit / Q8N1C3* / Q9R0Y8* / Gamma-aminobutyric acid receptor subunit gamma-1 *ENSDARG0000010199541
GABRA2 / gamma-aminobutyric acid type A receptor alpha2 subunit / P47869*ENSDARG0000011373735


Protein motifs (from Interpro)
Interpro ID Name
 IPR001390  Gamma-aminobutyric-acid A receptor, alpha subunit
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1902711 GABA-A receptor complex IBA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
GABA A receptor activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000078624 arhgef9b / Cdc42 guanine nucleotide exchange factor (GEF) 9b / O43307* / Q3UTH8* / ARHGEF9* / Rho guanine nucleotide exchange factor 9 * / Cdc42 guanine nucleotide exchange factor 9*  / complex
 ENSDARG00000061746 arhgef9a / Cdc42 guanine nucleotide exchange factor (GEF) 9a / O43307* / Q3UTH8* / ARHGEF9* / Rho guanine nucleotide exchange factor 9 * / Cdc42 guanine nucleotide exchange factor 9*  / complex






 

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