ENSDARG00000093125


Danio rerio

Features
Gene ID: ENSDARG00000093125
  
Biological name :RANBP2
  
Synonyms : RANBP2 / si:ch1073-55a19.2
  
Possible biological names infered from orthology : A6NKT7 / E3 SUMO-protein ligase RanBP2 / O14715 / P0DJD0 / P0DJD1 / P49792 / Q7Z3J3 / Q99666 / Q9ERU9 / RAN binding protein 2 / RANBP2-like and GRIP domain containing 1 / RANBP2-like and GRIP domain containing 2 / RANBP2-like and GRIP domain containing 3 / RANBP2-like and GRIP domain containing 4 / RANBP2-like and GRIP domain containing 5 / RANBP2-like and GRIP domain containing 6 / RANBP2-like and GRIP domain containing 8 / RGPD1 / RGPD2 / RGPD3 / RGPD4 / RGPD5 / RGPD6 / RGPD8
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 70157
Gene end: 94601
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000128025
Ensembl peptide - ENSDARP00000153036
Ensembl peptide - ENSDARP00000120327
NCBI entrez gene - 100317326     See in Manteia.
RefSeq - XM_002663280
swissprot - B8JMJ5
swissprot - X1WCS8
ZFIN ID - ZDB-GENE-081104-93
Ensembl - ENSDARG00000093125
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000016808Gallus gallus
 P49792ENSG00000153201Homo sapiens
 RGPD1ENSG00000187627Homo sapiens
 RGPD2ENSG00000185304Homo sapiens
 RGPD3ENSG00000153165Homo sapiens
 RGPD4ENSG00000196862Homo sapiens
 RGPD5ENSG00000015568Homo sapiens
 RGPD6ENSG00000183054Homo sapiens
 RGPD8ENSG00000169629Homo sapiens
 Q9ERU9ENSMUSG00000003226Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppie / peptidylprolyl isomerase E (cyclophilin E) / Q9QZH3* / Q9UNP9* / peptidylprolyl isomerase E* / Peptidyl-prolyl cis-trans isomerase E *ENSDARG000001032344
ppifb / peptidylprolyl isomerase Fb / PPIF* / P30405* / Q99KR7* / peptidylprolyl isomerase F* / Peptidyl-prolyl cis-trans isomerase F, mitochondrial *ENSDARG000000528423
ppiaa / peptidylprolyl isomerase Aa (cyclophilin A)ENSDARG000000092123
ppiab / peptidylprolyl isomerase Ab (cyclophilin A)ENSDARG000001039943
ppifa / peptidylprolyl isomerase FaENSDARG000000074093


Protein motifs (from Interpro)
Interpro ID Name
 IPR000156  Ran binding domain
 IPR001876  Zinc finger, RanBP2-type
 IPR002130  Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR011993  PH-like domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR020892  Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
 IPR022011  Nup358/RanBP2 E3 ligase domain
 IPR029000  Cyclophilin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IBA
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006405 RNA export from nucleus IBA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0007051 spindle organization IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046604 positive regulation of mitotic centrosome separation IBA
 biological_processGO:0046907 intracellular transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome IBA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0008536 Ran GTPase binding IBA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of Mature mRNA derived from an Intron-Containing Transcript
Regulation of Glucokinase by Glucokinase Regulatory Protein
snRNP Assembly
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
Transcriptional regulation by small RNAs
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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