Manteia

ENSDARG00000099351

Danio rerio

Features

Gene ID:	ENSDARG00000099351

Biological name :	igfbp1a

Synonyms :	igfbp1a / insulin-like growth factor binding protein 1a

Possible biological names infered from orthology :	IGFBP1 / insulin like growth factor binding protein 1 / P08833 / P47876

Species:	Danio rerio

Chr. number:	20
Strand:	-1
Band:
Gene start:	6808774
Gene end:	6812688

Corresponding Affymetrix probe sets:	Dr.8587.1.A1_at (Zebrafish Array) Dr.8587.1.A2_at (Zebrafish Array) NM_173283_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000135671 NCBI entrez gene - 317638 See in Manteia. RefSeq - NM_173283 RefSeq Peptide - NP_775390 swissprot - Q8JHX6 ZFIN ID - ZDB-GENE-021231-1 Ensembl - ENSDARG00000099351

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
igfbp1b / insulin-like growth factor binding protein 1b / P47876* / IGFBP1* / P08833* / insulin like growth factor binding protein 1*	ENSDARG00000038666	50
Q9PTH3 / igfbp2a / insulin-like growth factor binding protein 2a / IGFBP2* / P18065* / insulin like growth factor binding protein 2*	ENSDARG00000052470	30
igfbp5b / insulin-like growth factor binding protein 5b / Q07079* / IGFBP5* / P24593* / insulin like growth factor binding protein 5*	ENSDARG00000025348	30
igfbp5a / insulin-like growth factor binding protein 5a / IGFBP5* / P24593* / insulin like growth factor binding protein 5*	ENSDARG00000039264	29
igfbp2b / insulin-like growth factor binding protein 2b / P47877* / IGFBP2* / P18065* / insulin like growth factor binding protein 2*	ENSDARG00000031422	29
igfbp3 / insulin-like growth factor binding protein 3 / P17936* / P47878*	ENSDARG00000099144	27
igfbp6a / insulin-like growth factor binding protein 6a / IGFBP6* / P24592* / insulin like growth factor binding protein 6*	ENSDARG00000070941	23
igfbp6b / insulin-like growth factor binding protein 6b / IGFBP6* / P24592* / insulin like growth factor binding protein 6*	ENSDARG00000090833	21

Protein motifs (from Interpro)

Interpro ID	Name
IPR000716	Thyroglobulin type-1
IPR000867	Insulin-like growth factor-binding protein, IGFBP
IPR009030	Growth factor receptor cysteine-rich domain superfamily
IPR009168	Insulin-like growth factor binding protein
IPR017891	Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
IPR022321	Insulin-like growth factor-binding protein family 1-6, chordata
IPR022322	Insulin-like growth factor-binding protein 1

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001558	regulation of cell growth	IEA
biological_process	GO:0001666	response to hypoxia	IMP
biological_process	GO:0008285	negative regulation of cell proliferation	IDA
biological_process	GO:0031099	regeneration	IMP
biological_process	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	IBA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IBA
cellular_component	GO:0005737	cytoplasm	IDA
molecular_function	GO:0005520	insulin-like growth factor binding	IEA
molecular_function	GO:0031994	insulin-like growth factor I binding	IDA
molecular_function	GO:0031995	insulin-like growth factor II binding	IDA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr