Manteia

ENSDARG00000101735

Danio rerio

Features

Gene ID:	ENSDARG00000101735

Biological name :	chn1

Synonyms :	chimerin 1 / chn1

Possible biological names infered from orthology :	N-chimaerin / P15882 / Q91V57

Species:	Danio rerio

Chr. number:	9
Strand:	1
Band:
Gene start:	2393764
Gene end:	2487171

Corresponding Affymetrix probe sets:	Dr.7951.1.S1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000130201 Ensembl peptide - ENSDARP00000148244 NCBI entrez gene - 406273 See in Manteia. swissprot - Q5XIX9 swissprot - Q7ZUT6 ZFIN ID - ZDB-GENE-040426-1934 Ensembl - ENSDARG00000101735

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CHN1	ENSGALG00000009293	Gallus gallus
CHN1	ENSG00000128656	Homo sapiens
Chn1	ENSMUSG00000056486	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
chn2 / chimerin 2 / Q80XD1* / P52757* / AC004593.3* / Beta-chimaerin * / beta-chimaerin isoform 3 *	ENSDARG00000011845	72
arhgap21a / Rho GTPase activating protein 21a / Q5T5U3* / ARHGAP21* / Rho GTPase activating protein 21*	ENSDARG00000104295	26
arhgap21b / Rho GTPase activating protein 21b / Q5T5U3* / ARHGAP21* / Rho GTPase activating protein 21*	ENSDARG00000075673	26
arhgap12b / Rho GTPase activating protein 12b / Q8C0D4* / Q8IWW6* / ARHGAP12* / Rho GTPase activating protein 12*	ENSDARG00000026482	25
arhgap12a / Rho GTPase activating protein 12a / Q8C0D4* / Q8IWW6* / ARHGAP12* / Rho GTPase activating protein 12*	ENSDARG00000008548	25
bcr / breakpoint cluster region / P11274* / Q6PAJ1* / Breakpoint cluster region protein * / BCR, RhoGEF and GTPase activating protein*	ENSDARG00000079286	24
arhgap23a / Rho GTPase activating protein 23a / Q69ZH9* / Q9P227* / ARHGAP23* / Rho GTPase activating protein 23*	ENSDARG00000052950	23
si:dkey-91m11.5 / BCR* / P11274* / Q6PAJ1* / Breakpoint cluster region protein * / BCR, RhoGEF and GTPase activating protein*	ENSDARG00000042329	23
arhgap27 / Rho GTPase activating protein 27 / A2AB59* / Q6ZUM4*	ENSDARG00000104255	22
arhgap23b / Rho GTPase activating protein 23b / Q69ZH9* / Q9P227* / ARHGAP23* / Rho GTPase activating protein 23*	ENSDARG00000026840	22
arhgap27l / Rho GTPase activating protein 27, like / A2AB59* / Q6ZUM4* / ARHGAP27* / Rho GTPase activating protein 27*	ENSDARG00000061798	21
si:dkey-33c9.6	ENSDARG00000036420	18
CABZ01078415.1	ENSDARG00000077440	17
arhgap15 / Rho GTPase activating protein 15 / Q53QZ3* / Q811M1*	ENSDARG00000062349	17
CABZ01088367.1 / Q9BRR9* / ARHGAP9* / Rho GTPase activating protein 9*	ENSDARG00000013390	16
abr / active BCR-related / Q12979* / Q5SSL4* / active BCR-related gene*	ENSDARG00000095180	15
SYDE2 / synapse defective Rho GTPase homolog 2 / Q5VT97*	ENSDARG00000099479	15
CU928117.1	ENSDARG00000059587	6

Protein motifs (from Interpro)

Interpro ID	Name
IPR000198	Rho GTPase-activating protein domain
IPR000980	SH2 domain
IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR008936	Rho GTPase activation protein
IPR017356	Chimaerin
IPR020454	Diacylglycerol/phorbol-ester binding

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0021623	oculomotor nerve formation	IMP
biological_process	GO:0035556	intracellular signal transduction	IEA
biological_process	GO:0043547	positive regulation of GTPase activity	IDA
biological_process	GO:0051056	regulation of small GTPase mediated signal transduction	IEA
cellular_component	GO:0005622	intracellular	IEA
molecular_function	GO:0001565	phorbol ester receptor activity	IDA
molecular_function	GO:0005096	GTPase activator activity	IMP
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Rho GTPase cycle

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000405	cranial nerve III	cranial nerve III axon mislocalised , abnormal cranial nerve III axon extension process quality , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr