ENSMUSG00000056486


Mus musculus

Features
Gene ID: ENSMUSG00000056486
  
Biological name :Chn1
  
Synonyms : Chn1 / N-chimaerin / Q91V57
  
Possible biological names infered from orthology : chimerin 1 / P15882
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C3
Gene start: 73610660
Gene end: 73775346
  
Corresponding Affymetrix probe sets: 10483719 (MoGene1.0st)   1420545_a_at (Mouse Genome 430 2.0 Array)   1445691_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000116417
Ensembl peptide - ENSMUSP00000155037
Ensembl peptide - ENSMUSP00000137106
Ensembl peptide - ENSMUSP00000128847
Ensembl peptide - ENSMUSP00000123551
Ensembl peptide - ENSMUSP00000123312
Ensembl peptide - ENSMUSP00000116708
Ensembl peptide - ENSMUSP00000070301
Ensembl peptide - ENSMUSP00000099738
Ensembl peptide - ENSMUSP00000107655
Ensembl peptide - ENSMUSP00000115029
NCBI entrez gene - 108699     See in Manteia.
MGI - MGI:1915674
RefSeq - XM_006498561
RefSeq - NM_001113246
RefSeq - NM_001166603
RefSeq - NM_001166604
RefSeq - NM_029716
RefSeq - NM_175752
RefSeq - XM_006498557
RefSeq - XM_006498558
RefSeq - XM_006498560
RefSeq Peptide - NP_786928
RefSeq Peptide - NP_001106717
RefSeq Peptide - NP_001160075
RefSeq Peptide - NP_001160076
RefSeq Peptide - NP_083992
swissprot - B2FDI1
swissprot - B2FDI0
swissprot - A7VK14
swissprot - A7VK13
swissprot - Q91V57
swissprot - D6RCX8
swissprot - F7C3N6
swissprot - B2FDI2
Ensembl - ENSMUSG00000056486
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 chn1ENSDARG00000101735Danio rerio
 CHN1ENSGALG00000009293Gallus gallus
 CHN1ENSG00000128656Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chn2 / Q80XD1 / Beta-chimaerin / P52757* / chimerin 2* / AC004593.3* / beta-chimaerin isoform 3 *ENSMUSG0000000463373
Arhgap21 / Rho GTPase activating protein 21 / Q5T5U3*ENSMUSG0000003659127
Bcr / Q6PAJ1 / Breakpoint cluster region protein / P11274* / BCR, RhoGEF and GTPase activating protein*ENSMUSG0000000968124
A2AB59 / Arhgap27 / Rho GTPase activating protein 27 / Q6ZUM4*ENSMUSG0000003425524
Q8C0D4 / Arhgap12 / Rho GTPase activating protein 12 / Q8IWW6*ENSMUSG0000004122523
Q69ZH9 / Arhgap23 / Rho GTPase-activating protein 23 / Q9P227*ENSMUSG0000004980722
Abr / Q5SSL4 / active BCR-related gene / Q12979* / active BCR-related*ENSMUSG0000001763121
Arhgap9 / Rho GTPase activating protein 9 / Q9BRR9*ENSMUSG0000004034519
Q811M1 / Arhgap15 / Rho GTPase activating protein 15 / Q53QZ3*ENSMUSG0000004974419
Syde2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSMUSG0000003686318
Syde1 / synapse defective 1, Rho GTPase, homolog 1 (C. elegans) / Q6ZW31* / synapse defective Rho GTPase homolog 1*ENSMUSG0000003271417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000980  SH2 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein
 IPR017356  Chimaerin
 IPR020454  Diacylglycerol/phorbol-ester binding
 IPR035840  Chimaerin, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0050770 regulation of axonogenesis IDA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046875 ephrin receptor binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Arih2tm1.1(KOMP)Vlcg/Arih2+
Genetic Background: C57BL/6N-Arih2tm1.1(KOMP)Vlcg/Ucd

 MP:0000186 decreased circulating HDL cholesterol level "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Chn1mfy/Chn1mfy
Genetic Background: involves: C57BL/6

 MP:0000940 abnormal motor neuron innervation "misprojection or failure to bundle motor axons to an effector tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Chn1Gt714Lex/Chn1Gt714Lex
Genetic Background: involves: 129S5/SvEvBrd

 MP:0000955 abnormal spinal cord morphology "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Chn1tm1.1Ito/Chn1tm1.1Ito
Genetic Background: involves: C57BL/6NSlc

Allelic Composition: Chn1tm1Ito/Chn1tm1.1Ito,Tg(Slc17a6-icre)1Oki/0
Genetic Background: involves: C57BL/6 * C57BL/6NSlc

 MP:0001077 abnormal spinal nerve morphology "any anomaly, deformity, or malformation of the any of the 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Chn1Gt714Lex/Chn1Gt714Lex
Genetic Background: involves: 129S5/SvEvBrd

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: KitlSl-18H/KitlSl-con
Genetic Background: Not Specified

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Chn1tm2Abet/Chn1tm2Abet
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: LbrGt(XE569)Byg/LbrGt(XE569)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6Cr

 MP:0001396 unidirectional circling "circling behavior in one direction only, either clockwise or counterclockwise" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Chn1tm2Abet/Chn1tm2Abet
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Chn1mfy/Chn1mfy
Genetic Background: involves: C57BL/6

Allelic Composition: Chn1tm1.1Ito/Chn1tm1.1Ito
Genetic Background: involves: C57BL/6NSlc

Allelic Composition: Chn1Gt714Lex/Chn1Gt714Lex
Genetic Background: involves: 129S5/SvEvBrd

Allelic Composition: Chn1Gt714Lex/Chn1+,Epha4tm1Pch/Epha4+
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

Allelic Composition: Chn1tm1Ito/Chn1tm1.1Ito,Tg(Slc17a6-icre)1Oki/0
Genetic Background: involves: C57BL/6 * C57BL/6NSlc

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tnni3ktm1Tfo/Tnni3ktm1Tfo,A1cfTg(Myh6-cre/Esr1*)1Jmk/0
Genetic Background: involves: C57BL/6 * FVB/N

 MP:0002184 abnormal innervation "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0002272 abnormal nervous system electrophysiology "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Chn1mfy/Chn1mfy
Genetic Background: involves: C57BL/6

Allelic Composition: Chn1tm1.1Ito/Chn1tm1.1Ito
Genetic Background: involves: C57BL/6NSlc

 MP:0002590 increased mean corpuscular volume "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Arih2tm1.1(KOMP)Vlcg/Arih2+
Genetic Background: C57BL/6N-Arih2tm1.1(KOMP)Vlcg/Ucd

 MP:0002608 increased hematocrit "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0002826 tonic seizures "increased number or decreased threshold for the induction of a seizure characterized by muscle rigidity" [hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Chn1tm2Abet/Chn1tm2Abet
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0002878 abnormal corticospinal tract "anomaly in the structure or function of the fibers that arise from the cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Chn1mfy/Chn1mfy
Genetic Background: involves: C57BL/6

Allelic Composition: Chn1tm1.1Ito/Chn1tm1.1Ito
Genetic Background: involves: C57BL/6NSlc

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0003477 abnormal nerve fiber response "anomaly in the electrophysiological recordings from a single or several nerve fiber(s)" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Chn1tm1Ito/Chn1tm1.1Ito,Tg(Slc17a6-icre)1Oki/0
Genetic Background: involves: C57BL/6 * C57BL/6NSlc

 MP:0003651 abnormal axon outgrowth "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Chn1tm2Abet/Chn1tm2Abet
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0003880 abnormal central pattern generator function "anomalous function of the neural networks that produce rhythmic patterned output without sensory input and underlie rhythmic motor patterns" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:101019]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0004100 abnormal spinal cord interneuron morphology "malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Chn1Gt714Lex/Chn1Gt714Lex
Genetic Background: involves: 129S5/SvEvBrd

Allelic Composition: Chn1Gt714Lex/Chn1+,Epha4tm1Pch/Epha4+
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

 MP:0004145 abnormal muscle electrophysiology "anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Chn1Gt714Lex/Chn1Gt714Lex
Genetic Background: involves: 129S5/SvEvBrd

 MP:0004151 hypoferremia "less than the normal concentration of this metallic element in the blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0005564 increased hemoglobin content "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0005642 decreased mean corpuscular hemoglobin concentration "less than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0009677 abnormal spinal cord dorsal column morphology "any structural anomaly of the wedge-shaped fiber bundle of white matter in the dorsomedial side of the spinal cord that is made up of the fasciculus gracilis and fasciculus cuneatus; it is part of the ascending posterior column-medial lemniscus pathway that is important for well-localized fine touch and conscious proprioception" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN-10:0940780577 "Goldberg, S, Clinical Neuroanatomy Made Ridiculously Simple, 3rd edition"]
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Allelic Composition: Chn1mfy/Chn1mfy
Genetic Background: involves: C57BL/6

Allelic Composition: Chn1tm1.1Ito/Chn1tm1.1Ito
Genetic Background: involves: C57BL/6NSlc

Allelic Composition: Chn1Gt714Lex/Chn1+,Epha4tm1Pch/Epha4+
Genetic Background: involves: 129S2/SvPas * 129S5/SvEvBrd

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Chn1em1(IMPC)J/Chn1+
Genetic Background: C57BL/6NJ-Chn1em1(IMPC)J/J

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Cbln3tm1.1(KOMP)Vlcg/Cbln3tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cbln3tm1.1(KOMP)Vlcg/Ucd

 MP:0011380 enlarged brain ventricle "increased size of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:smb]
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Chn1tm2Abet/Chn1tm2Abet
Genetic Background: involves: 129P2/OlaHsd * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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