ENSMUSG00000049807


Mus musculus

Features
Gene ID: ENSMUSG00000049807
  
Biological name :Arhgap23
  
Synonyms : Arhgap23 / Q69ZH9 / Rho GTPase-activating protein 23
  
Possible biological names infered from orthology : Q9P227
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: D
Gene start: 97415533
Gene end: 97502402
  
Corresponding Affymetrix probe sets: 10380773 (MoGene1.0st)   1419745_at (Mouse Genome 430 2.0 Array)   1419746_at (Mouse Genome 430 2.0 Array)   1440614_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123191
Ensembl peptide - ENSMUSP00000091472
Ensembl peptide - ENSMUSP00000103227
Ensembl peptide - ENSMUSP00000112999
NCBI entrez gene - 58996     See in Manteia.
MGI - MGI:3697726
RefSeq - XM_006533874
RefSeq - XM_006533866
RefSeq - XM_006533867
RefSeq - XM_006533868
RefSeq - XM_006533869
RefSeq - XM_006533871
RefSeq - NM_021493
RefSeq - XM_006533861
RefSeq - XM_006533862
RefSeq - XM_006533863
RefSeq - XM_006533865
RefSeq Peptide - NP_067468
swissprot - F8VQ11
swissprot - D6RDB5
swissprot - B1AQY2
swissprot - Q69ZH9
Ensembl - ENSMUSG00000049807
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap23aENSDARG00000052950Danio rerio
 arhgap23bENSDARG00000026840Danio rerio
 ARHGAP23ENSGALG00000042628Gallus gallus
 Q9P227ENSG00000275832Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arhgap21 / Rho GTPase activating protein 21 / Q5T5U3*ENSMUSG0000003659139
Bcr / Q6PAJ1 / Breakpoint cluster region protein / P11274* / BCR, RhoGEF and GTPase activating protein*ENSMUSG0000000968112
A2AB59 / Arhgap27 / Rho GTPase activating protein 27 / Q6ZUM4*ENSMUSG0000003425512
Q8C0D4 / Arhgap12 / Rho GTPase activating protein 12 / Q8IWW6*ENSMUSG0000004122512
Syde2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSMUSG0000003686311
Syde1 / synapse defective 1, Rho GTPase, homolog 1 (C. elegans) / Q6ZW31* / synapse defective Rho GTPase homolog 1*ENSMUSG0000003271410
Abr / Q5SSL4 / active BCR-related gene / Q12979* / active BCR-related*ENSMUSG0000001763110
Arhgap9 / Rho GTPase activating protein 9 / Q9BRR9*ENSMUSG000000403459
Q811M1 / Arhgap15 / Rho GTPase activating protein 15 / Q53QZ3*ENSMUSG000000497449
Chn1 / Q91V57 / N-chimaerin / P15882* / chimerin 1*ENSMUSG000000564868
Chn2 / Q80XD1 / Beta-chimaerin / P52757* / chimerin 2* / AC004593.3* / beta-chimaerin isoform 3 *ENSMUSG000000046338


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001478  PDZ domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Apptm1b(KOMP)Wtsi/App+
Genetic Background: C57BL/6N-Apptm1b(KOMP)Wtsi/Ics

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Apptm1b(KOMP)Wtsi/App+
Genetic Background: C57BL/6N-Apptm1b(KOMP)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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