ENSG00000275832


Homo sapiens

Features
Gene ID: ENSG00000275832
  
Biological name :ARHGAP23
  
Synonyms : ARHGAP23 / Q9P227 / Rho GTPase activating protein 23
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 38419280
Gene end: 38512392
  
Corresponding Affymetrix probe sets: 226638_at (Human Genome U133 Plus 2.0 Array)   230013_s_at (Human Genome U133 Plus 2.0 Array)   230196_x_at (Human Genome U133 Plus 2.0 Array)   231903_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478142
Ensembl peptide - ENSP00000484509
Ensembl peptide - ENSP00000483748
Ensembl peptide - ENSP00000482992
Ensembl peptide - ENSP00000482982
Ensembl peptide - ENSP00000482425
Ensembl peptide - ENSP00000481862
Ensembl peptide - ENSP00000481292
NCBI entrez gene - 57636     See in Manteia.
OMIM - 610590
RefSeq - XM_017024902
RefSeq - XM_006721992
RefSeq - XM_006721993
RefSeq - XM_006721994
RefSeq - XM_011525073
RefSeq - XM_011525074
RefSeq - XM_011525075
RefSeq - XM_011525076
RefSeq - XM_011525077
RefSeq - NM_001199417
RefSeq - XM_006721991
RefSeq Peptide - NP_001186346
swissprot - A0A087WZ73
swissprot - A0A087WXU2
swissprot - A0A087WTU4
swissprot - A0A087X0Z0
swissprot - A0A087X1W6
swissprot - A0A087WZZ2
swissprot - Q9P227
Ensembl - ENSG00000275832
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap23aENSDARG00000052950Danio rerio
 arhgap23bENSDARG00000026840Danio rerio
 ARHGAP23ENSGALG00000042628Gallus gallus
 Q69ZH9ENSMUSG00000049807Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5T5U3 / ARHGAP21 / Rho GTPase activating protein 21ENSG0000010786342
Q8IWW6 / ARHGAP12 / Rho GTPase activating protein 12ENSG0000016532212
BCR / P11274 / BCR, RhoGEF and GTPase activating proteinENSG0000018671612
SYDE2 / Q5VT97 / synapse defective Rho GTPase homolog 2ENSG0000009709611
Q6ZUM4 / ARHGAP27 / Rho GTPase activating protein 27ENSG0000015931411
Q9BRR9 / ARHGAP9 / Rho GTPase activating protein 9ENSG0000012332910
ABR / Q12979 / active BCR-relatedENSG000001598429
SYDE1 / Q6ZW31 / synapse defective Rho GTPase homolog 1ENSG000001051379
CHN2 / P52757 / chimerin 2ENSG000001060698
Q53QZ3 / ARHGAP15 / Rho GTPase activating protein 15ENSG000000758848
CHN1 / P15882 / chimerin 1ENSG000001286568
AC004593.3 / beta-chimaerin isoform 3 ENSG000002851628


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001478  PDZ domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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