ENSG00000075884


Homo sapiens

Features
Gene ID: ENSG00000075884
  
Biological name :ARHGAP15
  
Synonyms : ARHGAP15 / Q53QZ3 / Rho GTPase activating protein 15
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q22.2
Gene start: 143091362
Gene end: 143768352
  
Corresponding Affymetrix probe sets: 218870_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390310
Ensembl peptide - ENSP00000295095
Ensembl peptide - ENSP00000386560
NCBI entrez gene - 55843     See in Manteia.
OMIM - 610578
RefSeq - XM_017004501
RefSeq - XM_011511483
RefSeq - XM_011511484
RefSeq - XM_017004499
RefSeq - XM_017004500
RefSeq - NM_018460
RefSeq - XM_011511479
RefSeq - XM_011511481
RefSeq - XM_011511482
RefSeq Peptide - NP_060930
swissprot - H7BZM0
swissprot - B8ZZK0
swissprot - Q53QZ3
Ensembl - ENSG00000075884
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap15ENSDARG00000062349Danio rerio
 Q5ZMM3ENSGALG00000012421Gallus gallus
 Q811M1ENSMUSG00000049744Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IWW6 / ARHGAP12 / Rho GTPase activating protein 12ENSG0000016532247
Q6ZUM4 / ARHGAP27 / Rho GTPase activating protein 27ENSG0000015931441
Q9BRR9 / ARHGAP9 / Rho GTPase activating protein 9ENSG0000012332937
Q5T5U3 / ARHGAP21 / Rho GTPase activating protein 21ENSG0000010786327
Q9P227 / ARHGAP23 / Rho GTPase activating protein 23ENSG0000027583226
ABR / Q12979 / active BCR-relatedENSG0000015984224
BCR / P11274 / BCR, RhoGEF and GTPase activating proteinENSG0000018671623
SYDE2 / Q5VT97 / synapse defective Rho GTPase homolog 2ENSG0000009709622
CHN2 / P52757 / chimerin 2ENSG0000010606918
CHN1 / P15882 / chimerin 1ENSG0000012865618
AC004593.3 / beta-chimaerin isoform 3 ENSG0000028516218
SYDE1 / Q6ZW31 / synapse defective Rho GTPase homolog 1ENSG0000010513718


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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