ENSG00000105137


Homo sapiens

Features
Gene ID: ENSG00000105137
  
Biological name :SYDE1
  
Synonyms : Q6ZW31 / SYDE1 / synapse defective Rho GTPase homolog 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.12
Gene start: 15107403
Gene end: 15114988
  
Corresponding Affymetrix probe sets: 212962_at (Human Genome U133 Plus 2.0 Array)   216271_x_at (Human Genome U133 Plus 2.0 Array)   216272_x_at (Human Genome U133 Plus 2.0 Array)   44702_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473151
Ensembl peptide - ENSP00000469489
Ensembl peptide - ENSP00000341489
Ensembl peptide - ENSP00000470733
Ensembl peptide - ENSP00000471553
NCBI entrez gene - 85360     See in Manteia.
OMIM - 617377
RefSeq - NM_001300910
RefSeq - NM_033025
RefSeq Peptide - NP_001287839
RefSeq Peptide - NP_149014
swissprot - Q6ZW31
swissprot - M0QXZ8
swissprot - M0R101
swissprot - M0R3D3
Ensembl - ENSG00000105137
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Syde1ENSMUSG00000032714Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYDE2 / Q5VT97 / synapse defective Rho GTPase homolog 2ENSG0000009709644
Q9P227 / ARHGAP23 / Rho GTPase activating protein 23ENSG0000027583219
Q5T5U3 / ARHGAP21 / Rho GTPase activating protein 21ENSG0000010786319
Q8IWW6 / ARHGAP12 / Rho GTPase activating protein 12ENSG0000016532215
Q6ZUM4 / ARHGAP27 / Rho GTPase activating protein 27ENSG0000015931415
BCR / P11274 / BCR, RhoGEF and GTPase activating proteinENSG0000018671615
ABR / Q12979 / active BCR-relatedENSG0000015984214
Q9BRR9 / ARHGAP9 / Rho GTPase activating protein 9ENSG0000012332914
Q53QZ3 / ARHGAP15 / Rho GTPase activating protein 15ENSG0000007588412
AC004593.3 / beta-chimaerin isoform 3 ENSG0000028516211
CHN2 / P52757 / chimerin 2ENSG0000010606911
CHN1 / P15882 / chimerin 1ENSG0000012865611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR008936  Rho GTPase activation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IBA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0051493 regulation of cytoskeleton organization IMP
 biological_processGO:0090630 activation of GTPase activity ISS
 biological_processGO:1901165 positive regulation of trophoblast cell migration IMP
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005096 GTPase activator activity TAS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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