ENSMUSG00000036591


Mus musculus

Features
Gene ID: ENSMUSG00000036591
  
Biological name :Arhgap21
  
Synonyms : Arhgap21 / Rho GTPase activating protein 21
  
Possible biological names infered from orthology : Q5T5U3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 20847919
Gene end: 20968881
  
Corresponding Affymetrix probe sets: 10480381 (MoGene1.0st)   1428368_at (Mouse Genome 430 2.0 Array)   1428369_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122497
Ensembl peptide - ENSMUSP00000123403
Ensembl peptide - ENSMUSP00000133851
Ensembl peptide - ENSMUSP00000133539
Ensembl peptide - ENSMUSP00000133347
Ensembl peptide - ENSMUSP00000110241
Ensembl peptide - ENSMUSP00000120357
Ensembl peptide - ENSMUSP00000122271
NCBI entrez gene - 71435     See in Manteia.
MGI - MGI:1918685
RefSeq - XM_017319263
RefSeq - XM_006497539
RefSeq - XM_006497540
RefSeq - XM_006497541
RefSeq - XM_006497542
RefSeq - XM_006497543
RefSeq - XM_006497544
RefSeq - XM_006497545
RefSeq - XM_011238986
RefSeq - XM_017319262
RefSeq - NM_001081364
RefSeq - NM_001128084
RefSeq - XM_006497538
RefSeq Peptide - NP_001121556
RefSeq Peptide - NP_001074833
swissprot - F6WQR2
swissprot - G3UWM5
swissprot - B7ZCJ0
swissprot - A0A0A0MQE8
swissprot - B7ZCJ1
swissprot - G3UX38
swissprot - A2BHQ2
Ensembl - ENSMUSG00000036591
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap21aENSDARG00000104295Danio rerio
 arhgap21bENSDARG00000075673Danio rerio
 ARHGAP21ENSGALG00000007721Gallus gallus
 Q5T5U3ENSG00000107863Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q69ZH9 / Arhgap23 / Rho GTPase-activating protein 23 / Q9P227*ENSMUSG0000004980725
Bcr / Q6PAJ1 / Breakpoint cluster region protein / P11274* / BCR, RhoGEF and GTPase activating protein*ENSMUSG0000000968110
Q8C0D4 / Arhgap12 / Rho GTPase activating protein 12 / Q8IWW6*ENSMUSG0000004122510
A2AB59 / Arhgap27 / Rho GTPase activating protein 27 / Q6ZUM4*ENSMUSG000000342559
Syde2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSMUSG000000368639
Abr / Q5SSL4 / active BCR-related gene / Q12979* / active BCR-related*ENSMUSG000000176317
Syde1 / synapse defective 1, Rho GTPase, homolog 1 (C. elegans) / Q6ZW31* / synapse defective Rho GTPase homolog 1*ENSMUSG000000327147
Chn1 / Q91V57 / N-chimaerin / P15882* / chimerin 1*ENSMUSG000000564866
Q811M1 / Arhgap15 / Rho GTPase activating protein 15 / Q53QZ3*ENSMUSG000000497446
Arhgap9 / Rho GTPase activating protein 9 / Q9BRR9*ENSMUSG000000403456
Chn2 / Q80XD1 / Beta-chimaerin / P52757* / chimerin 2* / AC004593.3* / beta-chimaerin isoform 3 *ENSMUSG000000046336


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001478  PDZ domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051683 establishment of Golgi localization IEA
 biological_processGO:0051684 maintenance of Golgi location IEA
 biological_processGO:0072384 organelle transport along microtubule IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr