ENSMUSG00000034255


Mus musculus

Features
Gene ID: ENSMUSG00000034255
  
Biological name :Arhgap27
  
Synonyms : A2AB59 / Arhgap27 / Rho GTPase activating protein 27
  
Possible biological names infered from orthology : Q6ZUM4
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 103331497
Gene end: 103363692
  
Corresponding Affymetrix probe sets: 10391895 (MoGene1.0st)   10391914 (MoGene1.0st)   1416758_at (Mouse Genome 430 2.0 Array)   1431313_at (Mouse Genome 430 2.0 Array)   1446455_at (Mouse Genome 430 2.0 Array)   1457655_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039427
Ensembl peptide - ENSMUSP00000128051
Ensembl peptide - ENSMUSP00000102639
Ensembl peptide - ENSMUSP00000102638
Ensembl peptide - ENSMUSP00000102637
NCBI entrez gene - 544817     See in Manteia.
MGI - MGI:1916903
RefSeq - XM_006533754
RefSeq - NM_001205236
RefSeq - NM_133715
RefSeq - NM_183288
RefSeq Peptide - NP_001192165
RefSeq Peptide - NP_899111
RefSeq Peptide - NP_598476
swissprot - A2AKN5
swissprot - A2AB70
swissprot - A2AB59
swissprot - E9Q6V8
Ensembl - ENSMUSG00000034255
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap27ENSDARG00000104255Danio rerio
 arhgap27lENSDARG00000061798Danio rerio
 Q6ZUM4ENSG00000159314Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8C0D4 / Arhgap12 / Rho GTPase activating protein 12 / Q8IWW6*ENSMUSG0000004122535
Arhgap9 / Rho GTPase activating protein 9 / Q9BRR9*ENSMUSG0000004034521
Q811M1 / Arhgap15 / Rho GTPase activating protein 15 / Q53QZ3*ENSMUSG0000004974421
Arhgap21 / Rho GTPase activating protein 21 / Q5T5U3*ENSMUSG0000003659121
Bcr / Q6PAJ1 / Breakpoint cluster region protein / P11274* / BCR, RhoGEF and GTPase activating protein*ENSMUSG0000000968119
Q69ZH9 / Arhgap23 / Rho GTPase-activating protein 23 / Q9P227*ENSMUSG0000004980718
Abr / Q5SSL4 / active BCR-related gene / Q12979* / active BCR-related*ENSMUSG0000001763117
Syde2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSMUSG0000003686317
Syde1 / synapse defective 1, Rho GTPase, homolog 1 (C. elegans) / Q6ZW31* / synapse defective Rho GTPase homolog 1*ENSMUSG0000003271413
Chn1 / Q91V57 / N-chimaerin / P15882* / chimerin 1*ENSMUSG0000005648613
Chn2 / Q80XD1 / Beta-chimaerin / P52757* / chimerin 2* / AC004593.3* / beta-chimaerin isoform 3 *ENSMUSG0000000463312


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001202  WW domain
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR011993  PH-like domain superfamily
 IPR036020  WW domain superfamily
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis ISS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity ISS
 cellular_componentGO:0005622 intracellular ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005096 GTPase activator activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017124 SH3 domain binding ISS


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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