ENSDARG00000011845


Danio rerio

Features
Gene ID: ENSDARG00000011845
  
Biological name :chn2
  
Synonyms : chimerin 2 / chn2
  
Possible biological names infered from orthology : AC004593.3 / Beta-chimaerin / beta-chimaerin isoform 3 / P52757 / Q80XD1
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 20318400
Gene end: 20492799
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000027417
Ensembl peptide - ENSDARP00000122731
NCBI entrez gene - 570999     See in Manteia.
swissprot - E7F3K5
swissprot - F1QT22
ZFIN ID - ZDB-GENE-091020-5
Ensembl - ENSDARG00000011845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011164Gallus gallus
 AC004593.3ENSG00000285162Homo sapiens
 CHN2ENSG00000106069Homo sapiens
 Chn2ENSMUSG00000004633Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chn1 / chimerin 1 / P15882*ENSDARG0000010173571
arhgap12b / Rho GTPase activating protein 12b / Q8C0D4* / Q8IWW6* / ARHGAP12* / Rho GTPase activating protein 12*ENSDARG0000002648225
arhgap21a / Rho GTPase activating protein 21a / Q5T5U3* / ARHGAP21* / Rho GTPase activating protein 21*ENSDARG0000010429525
arhgap21b / Rho GTPase activating protein 21b / Q5T5U3* / ARHGAP21* / Rho GTPase activating protein 21*ENSDARG0000007567325
arhgap12a / Rho GTPase activating protein 12a / Q8C0D4* / Q8IWW6* / ARHGAP12* / Rho GTPase activating protein 12*ENSDARG0000000854824
arhgap23a / Rho GTPase activating protein 23a / Q69ZH9* / Q9P227* / ARHGAP23* / Rho GTPase activating protein 23*ENSDARG0000005295022
arhgap27 / Rho GTPase activating protein 27 / A2AB59* / Q6ZUM4*ENSDARG0000010425522
arhgap27l / Rho GTPase activating protein 27, like / A2AB59* / Q6ZUM4* / ARHGAP27* / Rho GTPase activating protein 27*ENSDARG0000006179822
bcr / breakpoint cluster region / P11274* / Q6PAJ1* / Breakpoint cluster region protein * / BCR, RhoGEF and GTPase activating protein*ENSDARG0000007928622
arhgap23b / Rho GTPase activating protein 23b / Q69ZH9* / Q9P227* / ARHGAP23* / Rho GTPase activating protein 23*ENSDARG0000002684021
si:dkey-91m11.5 / BCR* / P11274* / Q6PAJ1* / Breakpoint cluster region protein * / BCR, RhoGEF and GTPase activating protein*ENSDARG0000004232921
arhgap15 / Rho GTPase activating protein 15 / Q53QZ3* / Q811M1*ENSDARG0000006234917
si:dkey-33c9.6ENSDARG0000003642016
CABZ01078415.1ENSDARG0000007744016
CABZ01088367.1 / Q9BRR9* / ARHGAP9* / Rho GTPase activating protein 9*ENSDARG0000001339015
SYDE2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSDARG0000009947915
abr / active BCR-related / Q12979* / Q5SSL4* / active BCR-related gene*ENSDARG0000009518014
CU928117.1ENSDARG000000595875


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000980  SH2 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008936  Rho GTPase activation protein
 IPR017356  Chimaerin
 IPR020454  Diacylglycerol/phorbol-ester binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IBA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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