ENSDARG00000079286


Danio rerio

Features
Gene ID: ENSDARG00000079286
  
Biological name :bcr
  
Synonyms : bcr / breakpoint cluster region
  
Possible biological names infered from orthology : BCR, RhoGEF and GTPase activating protein / Breakpoint cluster region protein / P11274 / Q6PAJ1
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 17110598
Gene end: 17261078
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000092056
Ensembl peptide - ENSDARP00000147366
NCBI entrez gene - 568320     See in Manteia.
swissprot - F1Q9E9
ZFIN ID - ZDB-GENE-040724-43
Ensembl - ENSDARG00000079286
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BCRENSGALG00000006695Gallus gallus
 BCRENSG00000186716Homo sapiens
 BcrENSMUSG00000009681Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-91m11.5 / BCR* / P11274* / Q6PAJ1* / Breakpoint cluster region protein * / BCR, RhoGEF and GTPase activating protein*ENSDARG0000004232971
CU928117.1ENSDARG0000005958728
si:dkey-33c9.6ENSDARG0000003642023
abr / active BCR-related / Q12979* / Q5SSL4* / active BCR-related gene*ENSDARG0000009518014
arhgap21a / Rho GTPase activating protein 21a / Q5T5U3* / ARHGAP21* / Rho GTPase activating protein 21*ENSDARG0000010429513
arhgap27 / Rho GTPase activating protein 27 / A2AB59* / Q6ZUM4*ENSDARG0000010425512
arhgap12b / Rho GTPase activating protein 12b / Q8C0D4* / Q8IWW6* / ARHGAP12* / Rho GTPase activating protein 12*ENSDARG0000002648212
arhgap21b / Rho GTPase activating protein 21b / Q5T5U3* / ARHGAP21* / Rho GTPase activating protein 21*ENSDARG0000007567312
arhgap27l / Rho GTPase activating protein 27, like / A2AB59* / Q6ZUM4* / ARHGAP27* / Rho GTPase activating protein 27*ENSDARG0000006179812
arhgap12a / Rho GTPase activating protein 12a / Q8C0D4* / Q8IWW6* / ARHGAP12* / Rho GTPase activating protein 12*ENSDARG0000000854811
arhgap23b / Rho GTPase activating protein 23b / Q69ZH9* / Q9P227* / ARHGAP23* / Rho GTPase activating protein 23*ENSDARG0000002684011
arhgap23a / Rho GTPase activating protein 23a / Q69ZH9* / Q9P227* / ARHGAP23* / Rho GTPase activating protein 23*ENSDARG0000005295011
CABZ01078415.1ENSDARG000000774409
SYDE2 / synapse defective Rho GTPase homolog 2 / Q5VT97*ENSDARG000000994799
arhgap15 / Rho GTPase activating protein 15 / Q53QZ3* / Q811M1*ENSDARG000000623498
chn2 / chimerin 2 / Q80XD1* / P52757* / AC004593.3* / Beta-chimaerin * / beta-chimaerin isoform 3 *ENSDARG000000118458
chn1 / chimerin 1 / P15882*ENSDARG000001017358
CABZ01088367.1 / Q9BRR9* / ARHGAP9* / Rho GTPase activating protein 9*ENSDARG000000133906


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000198  Rho GTPase-activating protein domain
 IPR000219  Dbl homology (DH) domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001849  Pleckstrin homology domain
 IPR008936  Rho GTPase activation protein
 IPR011993  PH-like domain superfamily
 IPR015123  Bcr-Abl oncoprotein oligomerisation


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0016020 membrane IBA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005096 GTPase activator activity IBA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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