ENSDARG00000104566


Danio rerio

Features
Gene ID: ENSDARG00000104566
  
Biological name :foxi1
  
Synonyms : forkhead box i1 / foxi1
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 43662980
Gene end: 43664682
  
Corresponding Affymetrix probe sets: Dr.20969.1.S1_at (Zebrafish Array)   NM_181735_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000133283
NCBI entrez gene - 353313     See in Manteia.
RefSeq - NM_181735
RefSeq Peptide - NP_859424
swissprot - A0A0R4II00
swissprot - Q6DG75
ZFIN ID - ZDB-GENE-030505-1
Ensembl - ENSDARG00000104566
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxi2 / forkhead box I2 / FOXI3* / Q6ZQN5* / A8MTJ6* / forkhead box I3*ENSDARG0000006971549
foxi3b / forkhead box I3b / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000000955044
foxi3a / forkhead box I3a / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000005592639
Q9DE25 / foxc1a / forkhead box C1a / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000009148125
foxa3 / forkhead box A3 / P35584* / P55318* / Hepatocyte nuclear factor 3-gamma *ENSDARG0000001278824
Q9DE24 / foxc1b / forkhead box C1b / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000005539824
foxa2 / forkhead box A2 / P35583* / Q9Y261* / Mus musculus forkhead box A2 (Foxa2), transcript variant 3, mRNA.*ENSDARG0000000341123
foxa1 / forkhead box A1ENSDARG0000010213822
foxl1 / forkhead box L1 / Q12952* / Q64731* / Forkhead box protein L1 *ENSDARG0000000813321
foxa / forkhead box A sequenceENSDARG0000008709420
foxl2a / forkhead box L2a / FOXL2* / O88470* / P58012* / forkhead box L2* / Forkhead box protein L2 *ENSDARG0000004218020
zgc:194189ENSDARG0000000801019
foxl2b / forkhead box L2b / FOXL2* / P58012* / forkhead box L2*ENSDARG0000006841719
foxb2 / forkhead box B2 / Q5VYV0* / Q64733* / Forkhead box protein B2 *ENSDARG0000003747517
foxb1b / forkhead box B1b / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000005365017
foxb1a / forkhead box B1a / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000008904217


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0009957 epidermal cell fate specification IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0030916 otic vesicle formation IMP
 biological_processGO:0043049 otic placode formation IMP
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0048890 lateral line ganglion development IMP
 biological_processGO:0060788 ectodermal placode formation IGI
 biological_processGO:0061550 cranial ganglion development IMP
 biological_processGO:0071599 otic vesicle development IMP
 biological_processGO:0071600 otic vesicle morphogenesis IMP
 biological_processGO:0071696 ectodermal placode development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle decreased size , abnormal
otic vesicle neuron differentiation decreased process quality , abnormal
otic vesicle neuroblast (sensu Vertebrata) poorly differentiated , abnormal
otic vesicle has fewer parts of type immature macula , abnormal
otic vesicle morphology , abnormal
otic vesicle split , abnormal
otic vesicle decreased distribution , abnormal
Show

 ZFA:0000076 swim bladder swim bladder absent , abnormal
Show

 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
pharyngeal arch 3-7 skeleton has fewer parts of type ceratobranchial cartilage , abnormal
Show

 ZFA:0000138 otic placode otic placode split , abnormal
otic placode absent , abnormal
otic placode decreased distribution , abnormal
otic placode spatial pattern , ameliorated
Show

 ZFA:0000217 inner ear inner ear quality , abnormal
inner ear decreased size , abnormal
inner ear split , abnormal
inner ear malformed , abnormal
inner ear duplicated , abnormal
inner ear has fewer parts of type otolith , abnormal
Show

 ZFA:0000368 integument integument physical object quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000547 mouth mouth structure , abnormal
Show

 ZFA:0000641 cranial nerve cranial nerve neuron projection physical object quality , abnormal
cranial nerve neuron projection displaced , abnormal
Show

 ZFA:0000672 hyomandibula hyomandibula hypoplastic , abnormal
Show

 ZFA:0000818 vagal neural crest vagal neural crest decreased distance hyoid neural crest , abnormal
Show

 ZFA:0001094 whole organism whole organism quality , abnormal
whole organism lacks parts or has fewer parts of type hyosymplectic cartilage , abnormal
whole organism dead , abnormal
whole organism lacks parts or has fewer parts of type otic vesicle , abnormal
whole organism viability , abnormal
Show

 ZFA:0001104 pharyngeal endoderm pharyngeal endoderm apoptotic , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk bent , abnormal
Show

 ZFA:0001128 pharyngeal pouch 1 pharyngeal pouch 1 apoptotic process increased process quality , abnormal
Show

 ZFA:0001130 pharyngeal pouch 2 pharyngeal pouch 2 apoptotic process increased process quality , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage mislocalised ventrally , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton malformed , abnormal
mandibular arch skeleton decreased size , abnormal
Show

 ZFA:0001228 pharyngeal arch 3 skeleton pharyngeal arch 3 skeleton absent , abnormal
Show

 ZFA:0001229 pharyngeal arch 7 skeleton pharyngeal arch 7 skeleton decreased size , abnormal
Show

 ZFA:0001230 pharyngeal arch 6 skeleton pharyngeal arch 6 skeleton decreased size , abnormal
Show

 ZFA:0001231 pharyngeal arch 4 skeleton pharyngeal arch 4 skeleton absent , abnormal
Show

 ZFA:0001232 pharyngeal arch 5 skeleton pharyngeal arch 5 skeleton decreased size , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch quality , abnormal
Show

 ZFA:0001276 pharyngeal arch 2 skeleton pharyngeal arch 2 skeleton quality , abnormal
pharyngeal arch 2 skeleton decreased size , abnormal
pharyngeal arch 2 skeleton malformed , abnormal
Show

 ZFA:0001291 facial ganglion facial ganglion absent , abnormal
Show

 ZFA:0001301 glossopharyngeal ganglion glossopharyngeal ganglion absent , abnormal
Show

 ZFA:0001306 pharyngeal arch pharyngeal arch has fewer parts of type neuron , abnormal
pharyngeal arch morphology , abnormal
pharyngeal arch anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001309 neurogenic placode neurogenic placode apoptotic process increased process quality , abnormal
Show

 ZFA:0001310 dorsolateral placode dorsolateral placode decreased distribution , abnormal
Show

 ZFA:0001313 ventral anterior lateral line ganglion ventral anterior lateral line ganglion absent , abnormal
Show

 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage hypoplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased length , abnormal
ceratohyal cartilage absent , abnormal
ceratohyal cartilage orientation ceratohyal cartilage , abnormal
ceratohyal cartilage increased thickness , abnormal
ceratohyal cartilage hypoplastic , abnormal
ceratohyal cartilage displaced , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage decreased size , abnormal
hyosymplectic cartilage malformed , abnormal
hyosymplectic cartilage aplastic , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage mislocalised posteriorly , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage decreased length , abnormal
pharyngeal arch cartilage mislocalised posteriorly , abnormal
Show

 ZFA:0001483 middle lateral line ganglion middle lateral line ganglion absent , abnormal
Show

 ZFA:0001500 auditory capsule auditory capsule decreased size , abnormal
auditory capsule hypoplastic , abnormal
Show

 ZFA:0001510 basihyal cartilage basihyal cartilage decreased length , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage bent , abnormal
ceratobranchial cartilage hypoplastic , abnormal
ceratobranchial cartilage decreased amount , abnormal
Show

 ZFA:0001606 pharyngeal arch 3 pharyngeal arch 3 hypoplastic , abnormal
Show

 ZFA:0001607 pharyngeal arch 4 pharyngeal arch 4 hypoplastic , abnormal
Show

 ZFA:0001612 pharyngeal arch 1 pharyngeal arch 1 aplastic , abnormal
Show

 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 orientation whole organism anterior-posterior axis, abnormal
Show

 ZFA:0001617 otolith otolith mislocalised , abnormal
otolith quality , abnormal
otolith decreased size , abnormal
Show

 ZFA:0001715 otic vesicle protrusion otic vesicle protrusion morphology , abnormal
Show

 ZFA:0001717 pillar of the semicircular canal pillar of the semicircular canal aplastic , abnormal
Show

 ZFA:0007059 neurogenic field neurogenic field apoptotic process increased process quality , abnormal
neurogenic field posterior region decreased amount , abnormal
Show

 ZFA:0007061 epibranchial field epibranchial field spatial pattern , ameliorated
epibranchial field decreased distribution , abnormal
Show

 ZFA:0007067 vagal ganglion vagal ganglion decreased size , abnormal
vagal ganglion lacks parts or has fewer parts of type vagal ganglion , abnormal
Show

 ZFA:0007068 otic epithelium otic epithelium decreased distribution , abnormal
Show

 ZFA:0009292 radial glial cell radial glial cell cell projection disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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