ENSDARG00000055398


Danio rerio

Features
Gene ID: ENSDARG00000055398
  
Biological name :foxc1b
  
Synonyms : forkhead box C1b / foxc1b / Q9DE24
  
Possible biological names infered from orthology : forkhead box C1 / Forkhead box protein C1 / FOXC1 / Q12948 / Q61572
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 26702377
Gene end: 26704331
  
Corresponding Affymetrix probe sets: Dr.19254.1.A1_at (Zebrafish Array)   NM_131729_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000072219
NCBI entrez gene - 79375     See in Manteia.
RefSeq - NM_131729
RefSeq Peptide - NP_571804
swissprot - Q9DE24
ZFIN ID - ZDB-GENE-010302-2
Ensembl - ENSDARG00000055398
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXC1ENSG00000054598Homo sapiens
 Foxc1ENSMUSG00000050295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9DE25 / foxc1a / forkhead box C1a / FOXC1* / Q12948* / Q61572* / forkhead box C1* / Forkhead box protein C1 *ENSDARG0000009148171
foxa1 / forkhead box A1ENSDARG0000010213824
foxa3 / forkhead box A3 / P35584* / P55318* / Hepatocyte nuclear factor 3-gamma *ENSDARG0000001278824
foxl1 / forkhead box L1 / Q12952* / Q64731* / Forkhead box protein L1 *ENSDARG0000000813322
foxa2 / forkhead box A2 / P35583* / Q9Y261* / Mus musculus forkhead box A2 (Foxa2), transcript variant 3, mRNA.*ENSDARG0000000341122
foxa / forkhead box A sequenceENSDARG0000008709422
foxl2a / forkhead box L2a / FOXL2* / O88470* / P58012* / forkhead box L2* / Forkhead box protein L2 *ENSDARG0000004218022
foxi1 / forkhead box i1ENSDARG0000010456621
foxl2b / forkhead box L2b / FOXL2* / P58012* / forkhead box L2*ENSDARG0000006841721
foxb1a / forkhead box B1a / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000008904221
foxi2 / forkhead box I2 / FOXI3* / Q6ZQN5* / A8MTJ6* / forkhead box I3*ENSDARG0000006971521
foxi3a / forkhead box I3a / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000005592620
foxi3b / forkhead box I3b / FOXI1* / Q12951* / Q922I5* / forkhead box I1* / Forkhead box protein I1 *ENSDARG0000000955019
foxb2 / forkhead box B2 / Q5VYV0* / Q64733* / Forkhead box protein B2 *ENSDARG0000003747519
foxb1b / forkhead box B1b / FOXB1* / Q64732* / Q99853* / forkhead box B1* / Forkhead box protein B1 *ENSDARG0000005365019
zgc:194189ENSDARG0000000801018


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IGI
 biological_processGO:0001755 neural crest cell migration IGI
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0043010 camera-type eye development IGI
 biological_processGO:0043114 regulation of vascular permeability IGI
 biological_processGO:0061300 cerebellum vasculature development IGI
 biological_processGO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain hydrocephalic , abnormal
brain hemorrhagic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system hemorrhagic , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta morphology , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000096 cardinal system cardinal system morphology , abnormal
Show

 ZFA:0000099 brain vasculature brain vasculature morphology , abnormal
brain vasculature neural crest cell decreased amount , abnormal
Show

 ZFA:0000100 cerebellum cerebellum vascular associated smooth muscle cell decreased amount , abnormal
Show

 ZFA:0000107 eye eye apoptotic , abnormal
eye decreased size , abnormal
eye hemorrhagic , abnormal
eye basement membrane morphology , abnormal
eye basement membrane disorganized , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0001073 axial vasculature axial vasculature decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001261 ventricular system ventricular system distended , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel aplastic , abnormal
intersegmental vessel increased branchiness , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus physical object quality , abnormal
Show

 ZFA:0001685 corneal stroma corneal stroma structure , abnormal
Show

 ZFA:0001687 corneal endothelium corneal endothelium aplastic , abnormal
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 ZFA:0005046 hyaloid vessel hyaloid vessel morphology , abnormal
hyaloid vessel dilated , abnormal
hyaloid vessel decreased amount , abnormal
hyaloid vessel branchiness , abnormal
hyaloid vessel blood vessel endothelial cell disorganized , abnormal
Show

 ZFA:0005249 vasculature vasculature broken , abnormal
Show

 ZFA:0005572 periocular mesenchyme periocular mesenchyme disorganized , abnormal
Show

 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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