| MP:0000060 | delayed bone ossification | "late onset of the formation of bone" [J:40203] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000075 | absent neurocranium | "missing bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000104 | abnormal sphenoid bone morphology | "malformed irregularly shaped bone of the base of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000107 | abnormal frontal bone morphology | "malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
Show
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0000149 | abnormal scapula morphology | "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000157 | abnormal sternum morphology | "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000158 | absent sternum | "missing long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62577] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0000159 | abnormal xiphoid process | "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000163 | abnormal cartilage morphology | "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Tsc1tm1Djk/Tsc1tm1Djk,Tg(Camk2a-cre)#Szi/0
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J * C57BL/6NTac * CBA
|
| MP:0000164 | abnormal cartilage development | "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000259 | abnormal vascular development | "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0000291 | enlarged pericardium | "extended fibroserous membrane covering the heart and beginning of the great vessels" [J:29971] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0000295 | poorly developed ventricular trabeculae | "retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000516 | abnormal urinary system morphology | "structural or developmental anomaly of any of the organs involved in the production or excretion of urine " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: MitfMi-Mee/Mitf+
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0000519 | hydronephrosis | "dilation of the pelvis and calices of one or both kidneys" [J:56641] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000520 | absent kidney | "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000527 | abnormal kidney development | "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000530 | abnormal kidney vasculature | "malformation or malfunctioning of the blood vessel network of the organ of excretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc] |
Show
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000536 | hydroureter | "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000547 | short limbs | "reduced average length of the extremities" [MGI:CLS, J:61509] |
Show
Allelic Composition: Ift140tm1b(KOMP)Wtsi/Ift140tm1b(KOMP)Wtsi
Genetic Background: involves: C57BL/6N
|
| MP:0000554 | abnormal carpal bone morphology | "malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000556 | abnormal hindlimb morphology | "malformation of the entire posterior extremities" [MGI:tc] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000559 | abnormal femur morphology | "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000783 | abnormal forebrain morphology | "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J
Allelic Composition: Foxc1hith/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000788 | abnormal cerebral cortex morphology | "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857] |
Show
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Foxc1hith/Foxc1hith,Tg(mI56i-lacZ)1Mekk/0
Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1hith/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000790 | abnormal stratification in cerebral cortex | "abnormal formation or pattern of the layers of the cerebral cortex " [J:64289, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J
Allelic Composition: Foxc1hith/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0000792 | abnormal cortical marginal zone morphology | |
Show
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
Show
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0000820 | abnormal choroid plexus morphology | "malformed or absent fringe of the tela choroidea of the cerebral ventricles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000823 | abnormal lateral ventricle morphology | "malformation or absence of cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000825 | dilated lateral ventricles | "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000826 | abnormal third ventricle morphology | "malformation or absence of the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000828 | abnormal fourth ventricle morphology | "malformed or absent irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind; it is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000854 | abnormal cerebellum development | "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000913 | abnormal brain development | "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000923 | abnormal roof plate morphology | "malformation or absence of a transient group of neuroepithelial cells located at the dorsal midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0000928 | incomplete cephalic closure | "arrest of the fusion of the cephalic neural folds" [J:12622] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0000955 | abnormal spinal cord morphology | "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0001092 | abnormal trigeminal ganglion morphology | "malformed group of sensory neuron cell bodies associated with the trigeminal nerve (fifth cranial nerve)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33038] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0001116 | small gonad | "reduced size of the testis or the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001126 | abnormal ovary morphology | "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Hmx3tm2Tlu/Hmx3tm2Tlu
Genetic Background: involves: 129 * C57BL/6J
|
| MP:0001127 | small ovary | "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001129 | impaired ovarian folliculogenesis | "a block in the formation of the spherical ovum in the ovary" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001131 | abnormal ovarian follicles | "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
Show
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0001302 | eyelids open at birth | "widely open eyes instead of closed at perinatal stage" [J:51966] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0001303 | abnormal lens morphology | "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203] |
Show
Allelic Composition: Hoxd13spdh/Hoxd13+
Genetic Background: B6C3Fe a/a-Hoxd13spdh/J
|
| MP:0001304 | cataracts | "complete or partial opacity of the lens" [J:65031] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
|
| MP:0001306 | small lens | "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001312 | abnormal cornea morphology | "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0001319 | irregularly shaped pupil | "shape defects in the aperture of the iris through which light rays enter the eye, usually circular " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001322 | abnormal iris morphology | "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001346 | abnormal lacrimal gland morphology | "malformation of the glands that secrete tears" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Hmx3tm2Tlu/Hmx3tm2Tlu
Genetic Background: involves: 129 * C57BL/6J
|
| MP:0001348 | abnormal lacrimal gland physiology | |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001688 | abnormal somite development | "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Tlr7rsq2/Y
Genetic Background: C57BL/6J-Tlr7rsq2
|
| MP:0001691 | abnormal somite shape | "atypical characteristic surface configuration of a segmental mass along the notochord of the developing embryo" [J:37888] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0001891 | hydroencephaly | "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Foxc1tm1.1Tsku/Foxc1tm1.1Tsku
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL * Tac:NIHBS
|
| MP:0001893 | non-obstructive hydrocephaly | "abnormal cerebrospinal fluid absorption where there is no obstruction to fluid flow in the ventricular system" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0001915 | intracranial hemorrhage | "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0001953 | respiratory failure | "cessation of or failure to commence breathing" [MGI:cls, J:60159] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002016 | ovarian cysts | "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxd13spdh/Hoxd13+
Genetic Background: B6C3Fe a/a-Hoxd13spdh/J
Allelic Composition: Foxc1tm1.1Tsku/Foxc1tm1.1Tsku
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL * Tac:NIHBS
|
| MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002114 | abnormal axial skeleton morphology | "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tsc1tm1Djk/Tsc1tm1Djk,Tg(Camk2a-cre)#Szi/0
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J * C57BL/6NTac * CBA
|
| MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hmx3tm2Tlu/Hmx3tm2Tlu
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tsc1tm1Djk/Tsc1tm1Djk,Tg(Camk2a-cre)#Szi/0
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J * C57BL/6NTac * CBA
|
| MP:0002160 | abnormal reproductive system morphology | "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: MitfMi-Mee/Mitf+
Genetic Background: involves: C57BL/6 * FVB
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cd109tm1Mat/Cd109tm1Mat
Genetic Background: B6.129S6-Cd109tm1Mat
|
| MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002190 | disorganized myocardium | "malformed or poorly developed cardiac muscle layers" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67044] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002192 | hydrops fetalis | "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002196 | acallosal | "absence of the commissural plate interconnecting the cortical hemispheres of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0002200 | abnormal brain ventricle/choroid plexus morphology | "malformation or absence of the brain ventricles or their associated choroid plexuses" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002256 | abnormal laryngeal cartilage morphology | "any structural anomaly of the cartilagenous structures that support the larynx" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002257 | abnormal arytenoid cartilage morphology | "any structural anomaly of the paired triangular cartilages located postlaterally at the level of the thyroid cartilage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002258 | abnormal cricoid cartilage morphology | "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002260 | abnormal thyroid cartilage morphology | "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002546 | mydriasis | "dilation of one or both pupils" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0002672 | abnormal branchial arch artery morphology | "malformation of the vessels formed within the five pairs of branchial arches in embryogenesis; in the adult, some of these vessels give rise to the great vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002746 | abnormal semilunar valve morphology | "malformation of the valves that gate the flow of blood from the ventricles into the aorta and pulmonary trunk" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82728] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002747 | abnormal aortic valve morphology | "malformation of the valve between the left ventricle and the ascending aorta" [J:82728, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002748 | abnormal pulmonary valve morphology | "malformation of the valve between the right ventricle and the pulmonary trunk" [J:82728, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0002823 | abnormal rib development | "anomalous formation of the bones forming the bony wall of the chest" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84754] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002825 | abnormal notochord | "malformation or absence of the axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0002982 | abnormal germ cell migration | "defects in the orderly movement of a germ cell, a cell specialized to produce haploid gametes, from one site to another during development" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0003048 | abnormal cervical vertebrae morphology | "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003068 | enlarged kidney | "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003072 | abnormal metatarsal bone morphology | "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003073 | abnormal metacarpal bone morphology | "anomaly in the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003091 | abnormal cell migration | "defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Dmdmdx-3Cv/Y,Utrntm1Ked/Utrntm1Ked
Genetic Background: involves: 129 * C3H/HeHa * C57BL * M. m. castaneus * M. m musculus
|
| MP:0003120 | abnormal tracheal cartilage | "any structural anomaly of the cartilaginous structures that support the trachea" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:97123] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003139 | patent ductus arteriosus | "failure of the fetal connection between the aorta and pulmonary artery to close within 24 hours after birth" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0003232 | abnormal forebrain development | "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: CHMU/LeJ
|
| MP:0003419 | delayed endochondral bone ossification | "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: CHMU/LeJ
|
| MP:0003446 | renal hypoplasia | "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0003574 | abnormal oviduct morphology | "malformation of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0003584 | bifid ureter | "cleft of the ureter into two parts or branches" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: C57BL/6 * CHMU/Le
|
| MP:0003648 | abnormal radial glial cell morphology | "anomalous structure, number, or composition of the supporting cells of the developing central nervous system that guide neuronal migration during development and exchange metabolites with developing and migrating neurons; these cells differentiate into astrocytes and some neuronal types in the adult" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0003672 | abnormal ureter development | "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003816 | abnormal pituitary gland development | "malformation or incomplete differentiation of the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:51160] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003817 | abnormal Rathke s pouch | "malformation or incomplete differentiation of a pouch of ectoderm that grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:51160] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0003827 | abnormal Wolffian duct morphology | "malformation of the transient embryonic tubes that empty into the cloca and degenerate in the male " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003861 | abnormal nervous system development | "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0003935 | abnormal craniofacial development | "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004017 | duplex kidney | "a kidney that is split into two separate collecting systems; there may be a duplex ureter or a single ureter; may present unilaterally or bilaterally" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: C57BL/6 * CHMU/Le
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004068 | dilated dorsal aorta | "an expansion in the volume of the dorsal region of the main trunk of the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004076 | abnormal vitelline vascular remodelling | "anomaly in the conversion of the primary (honeycomb-like) vascular plexus of the yolk sac into a mature vascular network" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0004077 | abnormal striatum morphology | "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004085 | abnormal heartbeat | "anomaly in the appearance of regularly spaced contractions of the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004157 | interrupted aortic arch | "complete discontinuation/blockage between the ascending and descending aorta; includes Type A, interruption distal to the subclavian artery that is ipsilateral to the second carotid artery, and Type B, interruption between second carotid artery and ipsilateral subclavian artery" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: CHMU/LeJ
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| MP:0004221 | abnormal iridocorneal angle | "any structural abnormality of the acute angle occurring between the iris and the cornea at the periphery of the anterior chamber of the eye" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * CAST/Ei
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004222 | synechia | "an adhesion of parts, especially involving the iris e.g. attachments of the iris to the trabecular meshwork and peripheral cornea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh
|
| MP:0004223 | hypoplastic trabecular meshwork | "reduced size of the pore-like structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [MESH:A09.371.060.932, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: B6.Cg-Foxc1tm1Blh
|
| MP:0004226 | absent Schlemm s canal | "absence of the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
|
| MP:0004272 | abnormal basement membrane morphology | "anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A10.272.220] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0004322 | abnormal sternebra morphology | "any structural anomaly of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004353 | abnormal deltoid tuberosity morphology | "any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004376 | absent frontal bone | "absence of the bone forming the forehead and roof of the eye orbit" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004462 | small basisphenoid bone | "reduced size of part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004599 | abnormal vertebral arch morphology | "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004600 | abnormal vertebral transverse process | "any structural anomaly of the bony protrusions on either side of the arch of a vertebrae at the point where the lamina joins the pedicle, between the superior and inferior articular processes; muscles and ligaments attach to these processes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004607 | abnormal cervical atlas morphology | "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004670 | small vertebral body | "decreased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004674 | thin ribs | "a more slender appearance of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004726 | abnormal nasal capsule morphology | "any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0004787 | abnormal dorsal aorta morphology | "any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004834 | ovary hemorrhage | "presence of bleeding in the ovary" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0004915 | abnormal Reichert s cartilage | "any structural abnormality of the cartilage found in the mesenchyme of the second pharyngeal arch in the embryo from which develop the stapes, styloid process, lesser horn and upper part of the body of the hyoid bone; its proximal end gives rise to the stylohyoid ligament" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0005099 | abnormal ciliary body morphology | "structural anomaly of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005104 | abnormal tarsus morphology | "malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0005193 | abnormal anterior eye segment morphology | "anomalous structure of any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005198 | abnormal aqueous drainage system morphology | "anomalies in the structures associated with drainage of the aqueous humor from the eye, these include the trabecular meshwork, Schlemm s canal, the uveoscleral network, and the aqueous veins " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: B6.Cg-Foxc1tm1Blh
|
| MP:0005199 | abnormal iris pigment epithelium | "anomaly in the epithelial layer of the iris composed of cells containing pigment granules " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005203 | abnormal trabecular meshwork morphology | "structural anomaly in the porelike structure surrounding the entire circumference of the anterior chamber through which aqueous humor circulates" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+,Tyrc-2J/Tyrc-2J
Genetic Background: B6.Cg-Tyrc-2J Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * CAST/Ei
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005204 | abnormal canal of Schlemm morphology | "structural anomaly in the vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * CAST/Ei
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005223 | abnormal anterior-posterior polarity of the somites | "anomalous development or formation of the somites along the axis that runs from the front to the back surface of the body
" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:72325] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005225 | abnormal vertebrae development | "anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: CHMU/LeJ
|
| MP:0005269 | abnormal occipital bone morphology | "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005301 | abnormal corneal endothelium morphology | "anomalous structure of the single layer of large flattened cells that cover the surface of the cornea" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0005353 | abnormal patella morphology | "anomalous structure of the large sesamoid bone that covers the anterior surface of the knee" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0005431 | oocyte depletion | "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005537 | abnormal cerebral aqueduct | "anomalous structure of the channel in the mesencephalon that connets the third and fourth ventricles" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0005542 | corneal vascularization | "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
|
| MP:0005602 | decreased angiogenesis | "reduced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0005623 | abnormal meninges | "anomaly in any of the membranes covering the spinal cord and brain, including the dura mater (external), arachnoid (middle), and pia mater (internal)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, smb:Susan M. Bello , Mouse Genome Informatics Curator, J:48079] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0006000 | abnormal corneal epithelium | "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006031 | abnormal branchial pouch morphology | "malfomation or anomaly in the series of grooves that form between the branchial arches; these endodermal evaginations develop into epithelial tissues and organs" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006064 | abnormal superior vena cava morphology | "structural malformation in the principal vein draining blood from the upper portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006226 | iris hypoplasia | "less than the normal number of cells in the iris" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006230 | iris stroma hypoplasia | "less than the normal number of cells in the iris stroma" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006241 | abnormal placement of pupils | "abnormal location of the pupil so that it is not in the center of the iris" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: 129S6/SvEvTac-Foxc1tm1Blh
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006250 | abnormal line of Schwalbe | "malformation of the thickened peripheral margin of the vitreous membrane of the cornea" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0006341 | small first branchial arch | "reduced size of the first branchial arch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006345 | absent second branchial arch | "missing the second branchial arch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006354 | abnormal fourth branchial arch artery morphology | "any structural anomaly of the vessels formed within the fourth pair of branchial arches in embryogenesis" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006386 | absent somites | "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0006419 | disorganized testis cords | "derangement of the pattern of the attachments derived from the primordial seminiferous cords that differentiate into seminiferous tubules in adolescence" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0008148 | abnormal rib-sternum attachment | "any anomaly in the in the normal joining of the ribs to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: CHMU/LeJ
|
| MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0008275 | failure of endochondral bone ossification | "failure to initiate or a block in the process of the formation of bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0008276 | failure of intramembranous bone ossification | "failure to initiate or a block in the process of the formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified; intramembranous ossification is the way flat bones are formed" [GO:0001957] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0008277 | abnormal sternum ossification | "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0008278 | failure of sternum ossification | "failure to initiate or a block in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: CHMU/LeJ
|
| MP:0008487 | abnormal mesonephros morphology | "any structural anomaly of the excretory organ of the embryo, collective Wolffian tubules, which forms the urogenital fold from which the reproductive organs develop" [MESH:A16.254.500] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0008547 | abnormal neocortex morphology | "any structural anomaly of the larger part of the mammalian cerebral cortex, distinguished from the allocortex by being composed of a larger number of nerve cells arranged in six layers" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.186.211.730.885.213.420] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
|
| MP:0008915 | fused carpal bones | "anomaly of the nine nodular bones of the joint between the forelimb bones and the front paws/hands resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0008919 | fused tarsal bones | "anomaly of the eight bones of the instep of the paw/foot resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0008969 | abnormal nasolacrimal duct morphology | "any structural anomaly of the paired channels leading from the lacrimal sacs to the inferior meatus of the nose, through which tears are conducted through the nasal cavity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0009003 | abnormal vibrissa number | "any anomaly in the number of the stiff hairs projecting from the face around the nose of most mammals which act as touch receptors" [MESH:A13.950, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
|
| MP:0009022 | abnormal brain meninges morphology | "any structural anomaly in any of the membranes covering the brain, including the dura mater (external), arachnoid (middle), and pia mater (internal)" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J
Allelic Composition: Foxc1hith/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
|
| MP:0009071 | short oviduct | "length reduction or truncation of the tube through which the ova pass from the ovary to the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0009093 | oocyte degeneration | "a retrogressive impairment of function or destruction of the female germ cells" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0009433 | polyovular ovarian follicle | "an ovarian follicle containing more than one oocyte (ovum)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
|
| MP:0009825 | cornea ulcer | "an area of tissue erosion in the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J
Allelic Composition: Foxc1hith/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0009967 | abnormal neuron proliferation | "any anomaly in the ability of a neuron to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac
Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J
Allelic Composition: Foxc1hith/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
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| MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010418 | perimembraneous ventricular septal defect | "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010502 | ventricle myocardium hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the ventricular part of the heart myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010526 | aortic arch coarctation | "a congenital focal constriction of the aortic arch" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010593 | thick aortic valve cusps | "an increase in the ratio of the aortic valve cusp thickness to the aortic wall thickness" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010595 | abnormal aortic valve cusp morphology | "any structural anomaly of the three fibrous triangular components and associated flap of the aortic valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010602 | abnormal pulmonary valve cusp morphology | "any structural anomaly of the three fibrous triangular components and associated flap of the pulmonary valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010605 | thick pulmonary valve cusps | "an increase in the ratio of the pulmonary valve cusp thickness to the pulmonary artery wall thickness" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010709 | absent anterior chamber | "absence of the space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens" [MESH:A09.371.060.067] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Foxc1tm1.1Tsku/Foxc1tm1.1Tsku
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL * Tac:NIHBS
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| MP:0010941 | abnormal foramen magnum morphology | "any structural anomaly of the large orifice in the occipital bone through which the spinal cord passes to the cranial cavity and becomes continuous with the medulla oblongata" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith] |
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Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0010980 | ectopic ureteric bud | "ureteric bud(s) are not located in the normal or expected position" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0010981 | abnormal branching involved in ureteric bud morphogenesis | "anomaly in the process in which the branching structure of the ureteric bud is generated and organized" [GO:0001658] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0011309 | abnormal kidney arterial blood vessel morphology | "any structural anomaly of the network of tubes that supply blood to the renal tissues" [MGI:csmith] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011311 | abnormal kidney venous blood vessel morphology | "any structural anomaly of the network of tubes that return blood from the renal tissues to the systemic circulation" [MGI:csmith] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011318 | abnormal right renal artery morphology | "any structural anomaly of the major vessel which arises off the side of the abdominal aorta, immediately below the superior mesenteric artery, and supplies the right kidney with blood" [MGI:csmith] |
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Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011364 | abnormal metanephros morphology | "any structural anomaly of the primordium of the permanent kidney, which develops later than and caudal to the mesonephros, from the mesonephric duct and nephrogenic cord; the metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine" [GO:0001656] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011410 | ectopic testis | "one or both of the testes located outside the normal pathway of descent into the scrotum" [MGI:anna] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011481 | anterior iris synechia | "adhesion of the iris to the cornea" [MGI:anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
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| MP:0011486 | ectopic ureter | "an abnormally placed opening of the ureter, either into the urinary bladder or at another site in the lower urinary or genital tract" [MGI:anna] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0011493 | double ureter | "two ureters open separately into the renal pelvis superiorly and drain separately into the urinary bladder or genital tract; if two ureteral buds arise from the Wolffian duct, a duplex kidney with complete ureteral duplication ensues" [http://emedicine.medscape.com/article/378075-overview, MGI:anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0011723 | ectopic neuron | "appearance of a neuron or group of neurons in a region where it is not normally found" [MGI:csmith] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
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| MP:0011727 | ectopic ovary | "appearance of an ovary in a region where it is not normally found (topographical anomaly)" [MGI:csmith] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011732 | decreased somite size | "reduced size of any of the segmental masses along the notochord of the developing embryo" [MGI:smb] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0011797 | blind ureter | "a ureter ending in a blind-ended segment or pouch" [MGI:anna] |
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Allelic Composition: Hoxa1tm2Mrc/Hoxa1tm2Mrc,Hoxa2tm1Mrc/Hoxa2tm1Mrc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0011835 | abnormal urogenital fold morphology | "any structural anomaly of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora" [MGI:anna] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0011962 | increased cornea thickness | "increased width of the cornea in the center plane" [MGI:csmith] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
Allelic Composition: Foxc1tm1.1Tsku/Foxc1tm1.1Tsku
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL * Tac:NIHBS
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| MP:0012176 | abnormal head development | "anomaly in the process in which the anatomical structures of the head are generated and organized" [GO:0060323] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0012184 | absent paraxial mesoderm | "absence or loss of the mesoderm normally found at either side of the midline embryonic notochord that, on segmentation, forms the paired somites." [MGI:anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0012513 | absent sternum body | "absence of the middle and longest portion of the sternum, lying between the manubrium superiorly and the xiphoid process inferiorly; the body of the sternum (gladiolus) is considerably lengthier, narrower, and thinner than the manubrium, attaining its greatest breadth close to the lower end" [MGI:anna] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0013200 | head mesenchyme hypoplasia | "underdevelopment or reduced size of the head mesenchyme, usually due to a reduced cell number" [MGI:anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013261 | absent epiglottis | "missing the most superior of the laryngeal cartilages, which is normally found at the root of the tongue and folds back over the entrance to the larynx during swallowing, preventing inhalation of food or drink " [MIG:anna] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0013440 | abnormal exorbital lacrimal gland morphology | "any structural anomaly of the large exorbital (extra-orbital) lacrimal glands that are located subcutaneously at the anteroventral base of the ear adjacent to the parotid gland" [ISBN:0123813611, MGI:Anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013474 | abnormal lacrimal gland branching morphogenesis | "anomaly of the lacrimal gland bud to repeatedly divide into lobules during development of the lacrimal gland; in mouse, the primary bud arises around E13.5 and extends caudally into the surrounding neural-crest derived periocular mesenchyme; branching is initiated between E15.5 and E16.5 from the tip of the lacrimal bud; by E18.5, the gland consists of an extensively branched exorbital lobe and a small intraocular lobe derived from a single branch of the proximal duct; branching and differentiation of lacrimal glands is complete by around eyelid opening" [MGI:Anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013605 | abnormal ovarian bursa morphology | "any structural anomaly of the peritoneal recess between the medial aspect of the ovary and the mesosalpinx" [MGI:Anna, UBERON:0012333] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013608 | abnormal ovarian cortex morphology | "any structural anomaly of the layer of the ovarian stroma lying immediately beneath the tunica albuginea, composed of connective tissue cells and fibers, among which are scattered primary and secondary (antral) follicles in various stages of development; the cortex varies in thickness according to the age of the individual, becoming thinner with advancing years; included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte; the zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle; also in the cortex is the corpus luteum derived from the follicles" [http://en.wikipedia.org/wiki/Ovary, http://medical-dictionary.thefreedictionary.com/cortex+of+ovary] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013609 | abnormal ovarian medulla morphology | "any structural anomaly of the highly vascular stroma found in the center of the ovary that forms from embryonic mesenchyme and contains blood vessels, lymphatic vessels, and nerves; this stroma forms the tissue of the hilum by which the ovarian ligament is attached, and through which the blood vessels enter; it does not contain any ovarian follicles" [http://en.wikipedia.org/wiki/Ovary, MGI:Anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013738 | abnormal testis tunica albuginea morphology | "any structural anomaly of the dense fibrous connective tissue layer that covers the testis" [MGI:Anna, PMID:16412416] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0013743 | ciliary body hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the thickened portion of the vascular tunic which lies between the choroid and the iris" [ISBN:0-683-40008-8, MGI:Anna] |
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Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
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| MP:0014153 | absent intraorbital lacrimal gland | "absence of the small intra-orbital lacrimal gland that, in mice, is normally located superficially at the lateral canthus, where both the lacrimal gland and Harderian gland ducts open" [MGI:Anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0014164 | abnormal ciliary process morphology | " any structural anomaly of any of the pigmented processes that radiate from the ciliary muscle and give attachments to ligaments supporting the lens of the eye; these processes increase in thickness as they advance from the orbiculus ciliaris to the external border of the iris, and together with the folds (plicae) in the furrows between them, constitute the corona ciliaris; ciliary processes produce aqueous humor" [http://www.medilexicon.com/medicaldictionary.php?s=processus+ciliaris] |
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Allelic Composition: Foxc1ch/Foxc1+
Genetic Background: CHMU/Le
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| MP:0020391 | radial glial endfoot detachment | "detachment of the radial glia cell endfoot from the pial basement membrane" [MGI:anna, PMID:17715063, PMID:23217742, PMID:24256719] |
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Allelic Composition: Foxc1hith/Foxc1hith
Genetic Background: involves: C57BL/6J * FVB/N
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| MP:0030026 | small Meckel s cartilage | "reduced size of the cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible and gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [MGI:anna] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0030302 | abnormal maxillary zygomatic process morphology | "any structural anomaly of the rough triangular eminence situated at the angle of separation of the anterior, zygomatic, and orbital surfaces; in front, it forms part of the anterior surface; behind, it is concave, and forms part of the infratemporal fossa; above, it is rough and serrated for articulation with the zygomatic bone; below, it presents the prominent arched border which marks the division between the anterior and infratemporal surfaces" [https://en.wikipedia.org/wiki/Zygomatic_process_of_maxilla] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0030318 | enlarged maxillary zygomatic process | "increased size of the rough triangular eminence situated at the angle of separation of the anterior, zygomatic, and orbital surfaces; in front, it forms part of the anterior surface; behind, it is concave, and forms part of the infratemporal fossa; above, it is rough and serrated for articulation with the zygomatic bone; below, it presents the prominent arched border which marks the division between the anterior and infratemporal surfaces" [MGI:anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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| MP:0030337 | enlarged third pharyngeal arch artery | "increased size of the third pharyngeal arch artery" [MGI:anna] |
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Allelic Composition: Foxc1tm1Blh/Foxc1+,Foxc2tm1Blh/Foxc2tm1Blh
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0030420 | short basicranium | "decreased length of the anterior and/or posterior portions of the skull base" [MGI:anna] |
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Allelic Composition: Foxc1ch/Foxc1ch
Genetic Background: involves: CBA * STOCK Tyrc f
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