ENSMUSG00000048377


Mus musculus

Features
Gene ID: ENSMUSG00000048377
  
Biological name :Foxi2
  
Synonyms : forkhead box I2 / Foxi2
  
Possible biological names infered from orthology : Q6ZQN5
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F3
Gene start: 135410308
Gene end: 135413622
  
Corresponding Affymetrix probe sets: 10558405 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000053641
NCBI entrez gene - 270004     See in Manteia.
MGI - MGI:3028075
RefSeq - NM_183193
RefSeq Peptide - NP_899016
swissprot - A2RTG9
Ensembl - ENSMUSG00000048377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxi2ENSDARG00000069715Danio rerio
 FOXI2ENSG00000186766Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Foxi1 / Q922I5 / Forkhead box protein I1 / Q12951* / forkhead box I1*ENSMUSG0000004786142
Foxi3 / forkhead box I3 / A8MTJ6*ENSMUSG0000005587442
Foxc2 / Q61850 / Forkhead box protein C2 / Q99958* / forkhead box C2*ENSMUSG0000004671428
Foxc1 / Q61572 / Forkhead box protein C1 / Q12948* / forkhead box C1*ENSMUSG0000005029528
Foxa2 / P35583 / Mus musculus forkhead box A2 (Foxa2), transcript variant 3, mRNA. / Q9Y261* / forkhead box A2*ENSMUSG0000003702525
Foxs1 / Q61574 / Forkhead box protein S1 / O43638* / forkhead box S1*ENSMUSG0000007467624
Foxa1 / P35582 / Hepatocyte nuclear factor 3-alpha / P55317* / forkhead box A1*ENSMUSG0000003545124
Foxl2 / O88470 / Forkhead box protein L2 / P58012* / forkhead box L2*ENSMUSG0000005039724
Foxl1 / Q64731 / Forkhead box protein L1 / Q12952* / forkhead box L1*ENSMUSG0000009708424
Foxa3 / P35584 / Hepatocyte nuclear factor 3-gamma / P55318* / forkhead box A3*ENSMUSG0000004089123
Foxb1 / Q64732 / Forkhead box protein B1 / Q99853* / forkhead box B1*ENSMUSG0000005924621
Foxb2 / Q64733 / Forkhead box protein B2 / Q5VYV0* / forkhead box B2*ENSMUSG0000005682919


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR018122  Fork head domain conserved site1
 IPR030456  Fork head domain conserved site 2
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001082 abnormal geniculate ganglion morphology "malformed group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
Show

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0001092 abnormal trigeminal ganglion morphology "malformed group of sensory neuron cell bodies associated with the trigeminal nerve (fifth cranial nerve)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33038]
Show

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Folh1tm1b(KOMP)Wtsi/Folh1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Folh1tm1b(KOMP)Wtsi/J

 MP:0003703 abnormal vestibulocochlear ganglion morphology "malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0003861 abnormal nervous system development "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Oca2p-7Btlr/Oca2p-7Btlr
Genetic Background: C57BL/6J-Oca2p-7Btlr

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Folh1tm1b(KOMP)Wtsi/Folh1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Folh1tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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