ENSDARG00000111805


Danio rerio

Features
Gene ID: ENSDARG00000111805
  
Biological name :timp4.1
  
Synonyms : timp4.1 / TIMP metallopeptidase inhibitor 4, tandem duplicate 1
  
Possible biological names infered from orthology : Q99727 / Q9JHB3 / TIMP4 / TIMP metallopeptidase inhibitor 4 / tissue inhibitor of metalloproteinase 4
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 691734
Gene end: 701305
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000146729
NCBI entrez gene - 101882922     See in Manteia.
swissprot - E7FEZ5
ZFIN ID - ZDB-GENE-100603-1
Ensembl - ENSDARG00000111805
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TIMP4ENSGALG00000004969Gallus gallus
 TIMP4ENSG00000157150Homo sapiens
 Timp4ENSMUSG00000030317Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
timp4.2 / TIMP metallopeptidase inhibitor 4, tandem duplicate 2ENSDARG0000010261736
timp4.3 / TIMP metallopeptidase inhibitor 4, tandem duplicate 3ENSDARG0000010079536
timp2a / TIMP metallopeptidase inhibitor 2a / TIMP2* / P16035* / TIMP metallopeptidase inhibitor 2* / tissue inhibitor of metalloproteinase 2*ENSDARG0000006122626
timp2b / TIMP metallopeptidase inhibitor 2b / TIMP2* / P16035* / TIMP metallopeptidase inhibitor 2*ENSDARG0000007526126


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR001820  Protease inhibitor I35 (TIMP)
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR015614  Metalloproteinase inhibitor 4
 IPR027465  Proteinase inhibitor I35b (TIMP), C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009725 response to hormone IBA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0034097 response to cytokine IBA
 biological_processGO:0043086 negative regulation of catalytic activity IBA
 biological_processGO:0051045 negative regulation of membrane protein ectodomain proteolysis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0002020 protease binding IBA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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