ENSGALG00000004969


Gallus gallus

Features
Gene ID: ENSGALG00000004969
  
Biological name :TIMP4
  
Synonyms : TIMP4 / TIMP metallopeptidase inhibitor 4
  
Possible biological names infered from orthology : Q99727 / Q9JHB3 / tissue inhibitor of metalloproteinase 4
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 4723485
Gene end: 4746527
  
Corresponding Affymetrix probe sets: GgaAffx.26374.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007955
Ensembl peptide - ENSGALP00000047778
Ensembl peptide - ENSGALP00000045333
NCBI entrez gene - 768711     See in Manteia.
RefSeq - XM_001232058
swissprot - A0A1D5P514
swissprot - A0A1D5NY77
swissprot - F1NIB5
Ensembl - ENSGALG00000004969
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 timp4.1ENSDARG00000111805Danio rerio
 TIMP4ENSG00000157150Homo sapiens
 Timp4ENSMUSG00000030317Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TIMP2 / metalloproteinase inhibitor 2 precursor / P16035* / TIMP metallopeptidase inhibitor 2* / tissue inhibitor of metalloproteinase 2*ENSGALG0000002707049
TIMP3 / P26652 / Metalloproteinase inhibitor 3 / P39876* / P35625* / TIMP metallopeptidase inhibitor 3* / tissue inhibitor of metalloproteinase 3*ENSGALG0000002862748


Protein motifs (from Interpro)
Interpro ID Name
 IPR001134  Netrin domain
 IPR001820  Protease inhibitor I35 (TIMP)
 IPR008993  Tissue inhibitor of metalloproteinases-like, OB-fold
 IPR027465  Proteinase inhibitor I35b (TIMP), C-terminal
 IPR030490  Tissue inhibitor of metalloproteinase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0009725 response to hormone IBA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0034097 response to cytokine IBA
 biological_processGO:0043086 negative regulation of catalytic activity IBA
 biological_processGO:0051045 negative regulation of membrane protein ectodomain proteolysis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0002020 protease binding IBA
 molecular_functionGO:0008191 metalloendopeptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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