ENSG00000011132


Homo sapiens

Features
Gene ID: ENSG00000011132
  
Biological name :APBA3
  
Synonyms : amyloid beta precursor protein binding family A member 3 / APBA3 / O96018
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 3750819
Gene end: 3761699
  
Corresponding Affymetrix probe sets: 205146_x_at (Human Genome U133 Plus 2.0 Array)   215148_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000315136
NCBI entrez gene - 9546     See in Manteia.
OMIM - 604262
RefSeq - XM_006722951
RefSeq - NM_004886
RefSeq - XM_006722950
RefSeq Peptide - NP_004877
swissprot - O96018
Ensembl - ENSG00000011132
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-40i7.5ENSDARG00000090675Danio rerio
 APBA3ENSGALG00000000740Gallus gallus
 Apba3ENSMUSG00000004931Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APBA1 / Q02410 / amyloid beta precursor protein binding family A member 1ENSG0000010728248
APBA2 / Q99767 / amyloid beta precursor protein binding family A member 2ENSG0000003405346


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR030531  Amyloid beta A4 precursor protein-binding family A member 3
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0043086 negative regulation of catalytic activity IDA
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0004857 enzyme inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000106089 STX1A / Q16623 / syntaxin 1A  / complex
 ENSG00000136854 P61764 / STXBP1 / syntaxin binding protein 1  / complex






 

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