ENSG00000107282


Homo sapiens

Features
Gene ID: ENSG00000107282
  
Biological name :APBA1
  
Synonyms : amyloid beta precursor protein binding family A member 1 / APBA1 / Q02410
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q21.12
Gene start: 69427530
Gene end: 69672306
  
Corresponding Affymetrix probe sets: 206679_at (Human Genome U133 Plus 2.0 Array)   228101_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486435
Ensembl peptide - ENSP00000265381
NCBI entrez gene - 320     See in Manteia.
OMIM - 602414
RefSeq - XM_017014670
RefSeq - NM_001163
RefSeq - XM_005251968
RefSeq - XM_011518617
swissprot - Q02410
swissprot - A0A0D9SFA9
Ensembl - ENSG00000107282
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apba1aENSDARG00000103848Danio rerio
 apba1bENSDARG00000074328Danio rerio
 APBA1ENSGALG00000015111Gallus gallus
 Apba1ENSMUSG00000024897Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APBA2 / Q99767 / amyloid beta precursor protein binding family A member 2ENSG0000003405348
APBA3 / O96018 / amyloid beta precursor protein binding family A member 3ENSG0000001113233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR030530  Amyloid beta A4 precursor protein-binding family A member 1
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007269 neurotransmitter secretion TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008088 axo-dendritic transport TAS
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0014047 glutamate secretion IEA
 biological_processGO:0014051 gamma-aminobutyric acid secretion IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0065003 protein-containing complex assembly TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Dopamine Neurotransmitter Release Cycle
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104863 LIN7B / Q9HAP6 / lin-7 homolog B, crumbs cell polarity complex component  / complex / reaction
 ENSG00000111052 LIN7A / O14910 / lin-7 homolog A, crumbs cell polarity complex component  / complex / reaction
 ENSG00000148943 LIN7C / Q9NUP9 / lin-7 homolog C, crumbs cell polarity complex component  / complex / reaction
 ENSG00000147044 CASK / O14936 / calcium/calmodulin dependent serine protein kinase  / reaction / complex






 

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