ENSG00000013561


Homo sapiens

Features
Gene ID: ENSG00000013561
  
Biological name :RNF14
  
Synonyms : Q9UBS8 / ring finger protein 14 / RNF14
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q31.3
Gene start: 141958328
Gene end: 141990291
  
Corresponding Affymetrix probe sets: 201823_s_at (Human Genome U133 Plus 2.0 Array)   201824_at (Human Genome U133 Plus 2.0 Array)   243345_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378028
Ensembl peptide - ENSP00000378027
Ensembl peptide - ENSP00000420837
Ensembl peptide - ENSP00000426832
Ensembl peptide - ENSP00000425361
Ensembl peptide - ENSP00000423420
Ensembl peptide - ENSP00000423294
Ensembl peptide - ENSP00000423273
Ensembl peptide - ENSP00000422650
Ensembl peptide - ENSP00000422527
Ensembl peptide - ENSP00000421780
Ensembl peptide - ENSP00000324956
Ensembl peptide - ENSP00000348462
Ensembl peptide - ENSP00000378022
NCBI entrez gene - 9604     See in Manteia.
OMIM - 605675
RefSeq - XM_017010077
RefSeq - NM_183401
RefSeq - XM_005268536
RefSeq - XM_005268537
RefSeq - XM_005268539
RefSeq - XM_005268540
RefSeq - XM_005268541
RefSeq - XM_005268542
RefSeq - XM_005268543
RefSeq - XM_011537714
RefSeq - XM_017010070
RefSeq - XM_017010071
RefSeq - XM_017010072
RefSeq - XM_017010073
RefSeq - XM_017010074
RefSeq - XM_017010075
RefSeq - XM_017010076
RefSeq - NM_001201365
RefSeq - NM_004290
RefSeq - NM_183398
RefSeq - NM_183399
RefSeq - NM_183400
RefSeq Peptide - NP_004281
RefSeq Peptide - NP_899645
RefSeq Peptide - NP_899646
RefSeq Peptide - NP_899647
RefSeq Peptide - NP_899648
RefSeq Peptide - NP_001188294
swissprot - D6RA38
swissprot - D6R996
swissprot - E7EP22
swissprot - Q9UBS8
swissprot - D6R988
swissprot - D6RDU6
swissprot - D6RDK2
swissprot - D6RBU3
swissprot - D6RBK4
swissprot - D6RAS4
Ensembl - ENSG00000013561
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf14ENSDARG00000043905Danio rerio
 RNF14 (1 of many)ENSDARG00000091727Danio rerio
 RNF14 (1 of many)ENSDARG00000104631Danio rerio
 zmp:0000000524ENSDARG00000078683Danio rerio
 RNF14ENSGALG00000043085Gallus gallus
 Rnf14ENSMUSG00000060450Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NV58 / RNF19A / ring finger protein 19A, RBR E3 ubiquitin protein ligaseENSG0000003467718
Q6ZMZ0 / RNF19B / ring finger protein 19BENSG0000011651416
P50876 / RNF144A / ring finger protein 144AENSG0000015169214
Q7Z419 / RNF144B / ring finger protein 144BENSG0000013739314


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR006575  RWD domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR017907  Zinc finger, RING-type, conserved site
 IPR031127  E3 ubiquitin ligase RBR family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0016567 protein ubiquitination IEP
 biological_processGO:0030521 androgen receptor signaling pathway NAS
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated NAS
 biological_processGO:0060765 regulation of androgen receptor signaling pathway IDA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019787 ubiquitin-like protein transferase activity IDA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050681 androgen receptor binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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