ENSG00000116514


Homo sapiens

Features
Gene ID: ENSG00000116514
  
Biological name :RNF19B
  
Synonyms : Q6ZMZ0 / ring finger protein 19B / RNF19B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.1
Gene start: 32936445
Gene end: 32964685
  
Corresponding Affymetrix probe sets: 213038_at (Human Genome U133 Plus 2.0 Array)   36564_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000235150
Ensembl peptide - ENSP00000349482
Ensembl peptide - ENSP00000362555
NCBI entrez gene - 127544     See in Manteia.
OMIM - 610872
RefSeq - XM_006710358
RefSeq - NM_001127361
RefSeq - NM_001300826
RefSeq - NM_153341
RefSeq - XM_006710356
RefSeq - XM_006710357
RefSeq Peptide - NP_001120833
RefSeq Peptide - NP_001287755
RefSeq Peptide - NP_699172
swissprot - Q6ZMZ0
Ensembl - ENSG00000116514
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf19bENSDARG00000060926Danio rerio
 RNF19BENSGALG00000039716Gallus gallus
 A2A7Q9ENSMUSG00000028793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NV58 / RNF19A / ring finger protein 19A, RBR E3 ubiquitin protein ligaseENSG0000003467756
P50876 / RNF144A / ring finger protein 144AENSG0000015169212
Q7Z419 / RNF144B / ring finger protein 144BENSG0000013739312
RNF14 / Q9UBS8 / ring finger protein 14ENSG0000001356110


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR031127  E3 ubiquitin ligase RBR family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0044194 cytolytic granule IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr