ENSG00000137393


Homo sapiens

Features
Gene ID: ENSG00000137393
  
Biological name :RNF144B
  
Synonyms : Q7Z419 / ring finger protein 144B / RNF144B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p22.3
Gene start: 18387350
Gene end: 18468874
  
Corresponding Affymetrix probe sets: 228153_at (Human Genome U133 Plus 2.0 Array)   235549_at (Human Genome U133 Plus 2.0 Array)   239012_at (Human Genome U133 Plus 2.0 Array)   239704_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000259939
NCBI entrez gene - 255488     See in Manteia.
RefSeq - NM_182757
RefSeq - XM_005248986
RefSeq Peptide - NP_877434
swissprot - Q7Z419
Ensembl - ENSG00000137393
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf144bENSDARG00000024940Danio rerio
 RNF144BENSGALG00000012683Gallus gallus
 Q8BKD6ENSMUSG00000038068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P50876 / RNF144A / ring finger protein 144AENSG0000015169253
Q9NV58 / RNF19A / ring finger protein 19A, RBR E3 ubiquitin protein ligaseENSG0000003467729
Q6ZMZ0 / RNF19B / ring finger protein 19BENSG0000011651429
RNF14 / Q9UBS8 / ring finger protein 14ENSG0000001356122


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR031127  E3 ubiquitin ligase RBR family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 cellular_componentGO:0000151 ubiquitin ligase complex IC
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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