ENSG00000151692


Homo sapiens

Features
Gene ID: ENSG00000151692
  
Biological name :RNF144A
  
Synonyms : P50876 / ring finger protein 144A / RNF144A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p25.1
Gene start: 6917392
Gene end: 7068286
  
Corresponding Affymetrix probe sets: 1570051_at (Human Genome U133 Plus 2.0 Array)   204040_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000414420
Ensembl peptide - ENSP00000321330
Ensembl peptide - ENSP00000402645
Ensembl peptide - ENSP00000411616
NCBI entrez gene - 9781     See in Manteia.
RefSeq - XM_017005404
RefSeq - XM_017005397
RefSeq - XM_017005398
RefSeq - XM_017005399
RefSeq - XM_017005400
RefSeq - XM_017005401
RefSeq - XM_017005402
RefSeq - XM_017005403
RefSeq - NM_001349182
RefSeq - NM_001349183
RefSeq - NM_001349184
RefSeq - NM_014746
RefSeq - XM_005246200
RefSeq - XM_005246202
RefSeq - XM_017005396
RefSeq Peptide - NP_055561
RefSeq Peptide - NP_001336111
RefSeq Peptide - NP_001336112
RefSeq Peptide - NP_001336113
swissprot - P50876
swissprot - H7C3G0
swissprot - C9JLH4
Ensembl - ENSG00000151692
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5RFV4ENSDARG00000020600Danio rerio
 rnf144abENSDARG00000042557Danio rerio
 RNF144AENSGALG00000028709Gallus gallus
 Q925F3ENSMUSG00000020642Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z419 / RNF144B / ring finger protein 144BENSG0000013739355
Q6ZMZ0 / RNF19B / ring finger protein 19BENSG0000011651429
Q9NV58 / RNF19A / ring finger protein 19A, RBR E3 ubiquitin protein ligaseENSG0000003467728
RNF14 / Q9UBS8 / ring finger protein 14ENSG0000001356122


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR002867  IBR domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR031127  E3 ubiquitin ligase RBR family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IBA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity EXP


Pathways (from Reactome)
Pathway description
E3 ubiquitin ligases ubiquitinate target proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000185651 P68036 / UBE2L3 / ubiquitin conjugating enzyme E2 L3  / reaction / complex
 ENSG00000253729 PRKDC / P78527 / protein kinase, DNA-activated, catalytic polypeptide  / complex / reaction






 

1 s.

 
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contact: otassy@igbmc.fr