ENSG00000019995


Homo sapiens

Features
Gene ID: ENSG00000019995
  
Biological name :ZRANB1
  
Synonyms : Q9UGI0 / zinc finger RANBP2-type containing 1 / ZRANB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.13
Gene start: 124942123
Gene end: 124988189
  
Corresponding Affymetrix probe sets: 225130_at (Human Genome U133 Plus 2.0 Array)   225131_at (Human Genome U133 Plus 2.0 Array)   225138_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352676
NCBI entrez gene - 54764     See in Manteia.
OMIM - 611749
RefSeq - XM_017016358
RefSeq - NM_017580
RefSeq - XM_006717907
RefSeq - XM_017016357
RefSeq - XM_005269925
RefSeq - XM_005269926
RefSeq Peptide - NP_060050
swissprot - Q9UGI0
Ensembl - ENSG00000019995
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zranb1aENSDARG00000060257Danio rerio
 ZRANB1ENSGALG00000031474Gallus gallus
 Q7M760ENSMUSG00000030967Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OTUD7A / Q8TE49 / OTU deubiquitinase 7AENSG0000016991817
OTUD7B / Q6GQQ9 / OTU deubiquitinase 7BENSG0000026452216
P21580 / TNFAIP3 / TNF alpha induced protein 3ENSG0000011850315


Protein motifs (from Interpro)
Interpro ID Name
 IPR001876  Zinc finger, RanBP2-type
 IPR003323  OTU domain
 IPR036443  Zinc finger, RanBP2-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007010 cytoskeleton organization IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0022604 regulation of cell morphogenesis IMP
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IMP
 biological_processGO:0035523 protein K29-linked deubiquitination IDA
 biological_processGO:0070536 protein K63-linked deubiquitination IMP
 biological_processGO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process IMP
 biological_processGO:1990168 protein K33-linked deubiquitination IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IMP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000134982 APC / P25054 / APC, WNT signaling pathway regulator  / reaction / complex
 ENSG00000175104 TRAF6 / Q9Y4K3 / TNF receptor associated factor 6  / complex






 

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