ENSG00000025156


Homo sapiens

Features
Gene ID: ENSG00000025156
  
Biological name :HSF2
  
Synonyms : heat shock transcription factor 2 / HSF2 / Q03933
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q22.31
Gene start: 122399546
Gene end: 122433119
  
Corresponding Affymetrix probe sets: 209657_s_at (Human Genome U133 Plus 2.0 Array)   211220_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357440
Ensembl peptide - ENSP00000400380
Ensembl peptide - ENSP00000477405
NCBI entrez gene - 3298     See in Manteia.
OMIM - 140581
RefSeq - NM_001135564
RefSeq - NM_004506
RefSeq Peptide - NP_001129036
RefSeq Peptide - NP_004497
swissprot - Q03933
swissprot - V9GZ44
Ensembl - ENSG00000025156
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hsf2ENSDARG00000053097Danio rerio
 HSF2ENSGALG00000038420Gallus gallus
 Hsf2ENSMUSG00000019878Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSF1 / Q00613 / heat shock transcription factor 1ENSG0000018512234
HSF4 / Q9ULV5 / heat shock transcription factor 4ENSG0000010287824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000232  Heat shock factor (HSF)-type, DNA-binding
 IPR010542  Vertebrate heat shock transcription factor, C-terminal domain
 IPR027712  Heat shock factor protein 2
 IPR027725  Heat shock transcription factor family
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr