| MP:0000825 | dilated lateral ventricles | "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
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| MP:0000827 | dilated third ventricle | "enlarged narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
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| MP:0001131 | abnormal ovarian follicles | "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001134 | absent corpora lutea | "missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001146 | abnormal testis morphology | "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)
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| MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001153 | small seminiferous tubules | "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)
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| MP:0001916 | intracerebral hemorrhage | "bleeding within the cerebrum" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
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| MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0001929 | abnormal gametogenesis | "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324] |
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Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)
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| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0002161 | abnormal fertility/fecundity | "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Plcg2al/Plcg2al
Genetic Background: involves: 129 * C57BL/6
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| MP:0002216 | abnormal seminiferous tubule morphology | "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0002682 | reduced number of mature ovarian follicles | "fewer than normal numbers of spehroidal cell aggregations in the ovary containing the ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0003718 | maternal effect | "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0004834 | ovary hemorrhage | "presence of bleeding in the ovary" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0004901 | decreased male germ cell number | "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
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| MP:0004929 | decreased epididymis weight | "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0005159 | azoospermia | "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0005169 | abnormal male meiosis | "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0005431 | oocyte depletion | "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0005560 | decreased circulating glucose level | "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H
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| MP:0005633 | increased circulating sodium level | "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Golga3tm1b(EUCOMM)Hmgu/Golga3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Golga3tm1b(EUCOMM)Hmgu/H
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| MP:0006361 | abnormal female germ cell morphology | "any structural anomaly female germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0008261 | arrest of male meiosis | "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0008280 | male germ cell apoptosis | "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0008283 | small hippocampus | "reduced size of the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0008535 | enlarged lateral ventricles | "increased size of the cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MESH:A08.186.211.276.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0008536 | enlarged third ventricle | "increased size of the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [MESH:A08.186.211.276.840, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0009444 | ovarian follicular cyst | "a sac filled with fluid that may develop when the structure containing the egg fails to break open at the time of ovulation" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0009452 | abnormal synaptonemal complex | "an anomaly in the formation of the proteinaceous structure involved in the pairing of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hsf2tm1Mmr/Hsf2tm1Mmr
Genetic Background: involves: 129S2/SvPas * C57BL/6
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0012681 | collapsed brain ventricles | "the luminal space of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord are severely reduced in volume or area, possibly due to reduced or absent cerebrospinal fluid production; collapsed ventricles can be a sign of increased intracranial pressure and accumulation of water in the brain parenchyma" [MGI:anna] |
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Allelic Composition: Adam15tm1Bbl/Adam15tm1Bbl
Genetic Background: B6.129X1-Adam15tm1Bbl
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| MP:0020550 | multinucleated giant male germ cells | "presence of large cells containing multiple nuclei formed abnormal opening of the cytoplasmic bridges that are part of normal germ cell division" [PMID:16272280, url:https://ntp.niehs.nih.gov/nnl/male_reproductive/testis/setubmgcel/index.htm] |
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Allelic Composition: Hsf1tm1Miv/Hsf1tm1Miv,Hsf2tm1Miv/Hsf2tm1Miv
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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