ENSG00000075618


Homo sapiens

Features
Gene ID: ENSG00000075618
  
Biological name :FSCN1
  
Synonyms : fascin actin-bundling protein 1 / FSCN1 / Q16658
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.1
Gene start: 5592823
Gene end: 5606655
  
Corresponding Affymetrix probe sets: 201564_s_at (Human Genome U133 Plus 2.0 Array)   210933_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000371798
Ensembl peptide - ENSP00000409967
Ensembl peptide - ENSP00000404506
Ensembl peptide - ENSP00000383982
NCBI entrez gene - 6624     See in Manteia.
OMIM - 602689
RefSeq - NM_003088
RefSeq Peptide - NP_003079
swissprot - C9JPH9
swissprot - C9JFC0
swissprot - A0A0A0MSB2
swissprot - Q16658
Ensembl - ENSG00000075618
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fscn1aENSDARG00000059680Danio rerio
 fscn1bENSDARG00000037747Danio rerio
 FSCN1ENSGALG00000021128Gallus gallus
 Fscn1ENSMUSG00000029581Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FSCN2 / O14926 / fascin actin-bundling protein 2, retinalENSG0000018676556
FSCN3 / Q9NQT6 / fascin actin-bundling protein 3ENSG0000010632827


Protein motifs (from Interpro)
Interpro ID Name
 IPR008999  Actin-crosslinking
 IPR010431  Fascin
 IPR022768  Fascin domain
 IPR024703  Fascin, metazoans
 IPR030146  Fascin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007043 cell-cell junction assembly IDA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0010592 positive regulation of lamellipodium assembly IDA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030035 microspike assembly IMP
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0032534 regulation of microvillus assembly IDA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IDA
 biological_processGO:0035089 establishment of apical/basal cell polarity IDA
 biological_processGO:0048870 cell motility IDA
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051491 positive regulation of filopodium assembly IMP
 biological_processGO:0071803 positive regulation of podosome assembly IDA
 biological_processGO:0090091 positive regulation of extracellular matrix disassembly IDA
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0001726 ruffle IDA
 cellular_componentGO:0002102 podosome IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0031253 cell projection membrane IDA
 cellular_componentGO:0031941 filamentous actin IBA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0044393 microspike IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071437 invadopodium IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr