ENSGALG00000021128


Gallus gallus

Features
Gene ID: ENSGALG00000021128
  
Biological name :FSCN1
  
Synonyms : fascin / FSCN1
  
Possible biological names infered from orthology : fascin actin-bundling protein 1 / Q16658 / Q61553
  
Species: Gallus gallus
  
Chr. number: 14
Strand: 1
Band:
Gene start: 4206721
Gene end: 4212949
  
Corresponding Affymetrix probe sets: Gga.9986.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000033359
Ensembl peptide - ENSGALP00000044196
NCBI entrez gene - 416485     See in Manteia.
RefSeq - NM_001178132
RefSeq Peptide - NP_001171603
swissprot - A0A1D6UPS2
swissprot - A0A1D5NV23
Ensembl - ENSGALG00000021128
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fscn1aENSDARG00000059680Danio rerio
 fscn1bENSDARG00000037747Danio rerio
 FSCN1ENSG00000075618Homo sapiens
 Fscn1ENSMUSG00000029581Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FSCN2 / fascin actin-bundling protein 2, retinal / O14926* / Q32M02* / Fascin-2 *ENSGALG0000002335449


Protein motifs (from Interpro)
Interpro ID Name
 IPR008999  Actin-crosslinking
 IPR010431  Fascin
 IPR022768  Fascin domain
 IPR024703  Fascin, metazoans
 IPR030146  Fascin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0007043 cell-cell junction assembly IEA
 biological_processGO:0010592 positive regulation of lamellipodium assembly IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030035 microspike assembly IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0032534 regulation of microvillus assembly IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0035089 establishment of apical/basal cell polarity IEA
 biological_processGO:0048870 cell motility IEA
 biological_processGO:0051017 actin filament bundle assembly IEA
 biological_processGO:0051491 positive regulation of filopodium assembly IEA
 biological_processGO:0071803 positive regulation of podosome assembly IEA
 biological_processGO:0090091 positive regulation of extracellular matrix disassembly IEA
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005902 microvillus IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0031253 cell projection membrane IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0044393 microspike IEA
 cellular_componentGO:0071437 invadopodium IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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