ENSG00000076108


Homo sapiens

Features
Gene ID: ENSG00000076108
  
Biological name :BAZ2A
  
Synonyms : BAZ2A / bromodomain adjacent to zinc finger domain 2A / Q9UIF9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.3
Gene start: 56595596
Gene end: 56636816
  
Corresponding Affymetrix probe sets: 201353_s_at (Human Genome U133 Plus 2.0 Array)   201354_s_at (Human Genome U133 Plus 2.0 Array)   201355_s_at (Human Genome U133 Plus 2.0 Array)   215437_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449473
Ensembl peptide - ENSP00000448760
Ensembl peptide - ENSP00000449496
Ensembl peptide - ENSP00000368754
Ensembl peptide - ENSP00000446880
Ensembl peptide - ENSP00000447248
Ensembl peptide - ENSP00000447314
Ensembl peptide - ENSP00000447591
Ensembl peptide - ENSP00000447941
NCBI entrez gene - 11176     See in Manteia.
OMIM - 605682
RefSeq - XM_017018742
RefSeq - XM_011537798
RefSeq - XM_011537799
RefSeq - XM_011537800
RefSeq - XM_011537801
RefSeq - XM_011537803
RefSeq - XM_011537804
RefSeq - XM_011537805
RefSeq - XM_011537806
RefSeq - XM_011537807
RefSeq - XM_011537809
RefSeq - XM_017018740
RefSeq - XM_017018741
RefSeq - NM_001300905
RefSeq - NM_001351156
RefSeq - NM_013449
RefSeq - XM_011537797
RefSeq Peptide - NP_038477
RefSeq Peptide - NP_001287834
RefSeq Peptide - NP_001338085
swissprot - H0YHL2
swissprot - H0YHQ7
swissprot - H0YII3
swissprot - F8VU39
swissprot - Q9UIF9
swissprot - A0A0C4DGI9
swissprot - J3KPG5
swissprot - F8VWQ3
swissprot - F8W053
Ensembl - ENSG00000076108
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 baz2aENSDARG00000102974Danio rerio
 BAZ2AENSGALG00000029588Gallus gallus
 Baz2aENSMUSG00000040054Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BAZ2B / Q9UIF8 / bromodomain adjacent to zinc finger domain 2BENSG0000012363633
BAZ1A / Q9NRL2 / bromodomain adjacent to zinc finger domain 1AENSG0000019860416
BAZ1B / Q9UIG0 / bromodomain adjacent to zinc finger domain 1BENSG0000000995415
CREBBP / Q92793 / CREB binding proteinENSG0000000533911
EP300 / Q09472 / E1A binding protein p300ENSG0000010039311
BRD4 / O60885 / bromodomain containing 4ENSG000001418678
BRDT / Q58F21 / bromodomain testis associatedENSG000001379487
BRD2 / P25440 / bromodomain containing 2ENSG000002042566
BRD3 / Q15059 / bromodomain containing 3ENSG000001699256


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR001739  Methyl-CpG DNA binding
 IPR001965  Zinc finger, PHD-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016177  DNA-binding domain superfamily
 IPR017956  AT hook, DNA-binding motif
 IPR018359  Bromodomain, conserved site
 IPR018501  DDT domain
 IPR019787  Zinc finger, PHD-finger
 IPR028940  Bromodomain adjacent to zinc finger domain protein 2A
 IPR028941  WHIM2 domain
 IPR028942  WHIM1 domain
 IPR036427  Bromodomain-like superfamily
 IPR037374  BAZ2A/BAZ2B, bromodomain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000183 chromatin silencing at rDNA ISS
 biological_processGO:0001188 RNA polymerase I transcriptional preinitiation complex assembly IEA
 biological_processGO:0006306 DNA methylation ISS
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling NAS
 biological_processGO:0006351 transcription, DNA-templated NAS
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0016575 histone deacetylation ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005677 chromatin silencing complex ISS
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0033553 rDNA heterochromatin ISS
 molecular_functionGO:0001164 RNA polymerase I CORE element sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016922 nuclear receptor binding NAS
 molecular_functionGO:0042393 histone binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070577 lysine-acetylated histone binding ISS


Pathways (from Reactome)
Pathway description
NoRC negatively regulates rRNA expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000153147 O60264 / SMARCA5 / SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5  / complex






 

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