ENSG00000137948


Homo sapiens

Features
Gene ID: ENSG00000137948
  
Biological name :BRDT
  
Synonyms : BRDT / bromodomain testis associated / Q58F21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.1
Gene start: 91949371
Gene end: 92014426
  
Corresponding Affymetrix probe sets: 206787_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000400199
Ensembl peptide - ENSP00000400002
Ensembl peptide - ENSP00000404969
Ensembl peptide - ENSP00000447394
Ensembl peptide - ENSP00000446599
Ensembl peptide - ENSP00000416714
Ensembl peptide - ENSP00000414349
Ensembl peptide - ENSP00000410587
Ensembl peptide - ENSP00000408625
Ensembl peptide - ENSP00000408138
Ensembl peptide - ENSP00000354568
Ensembl peptide - ENSP00000359416
Ensembl peptide - ENSP00000378038
Ensembl peptide - ENSP00000384051
Ensembl peptide - ENSP00000387822
Ensembl peptide - ENSP00000396351
NCBI entrez gene - 676     See in Manteia.
OMIM - 602144
RefSeq - XM_011542036
RefSeq - NM_001242805
RefSeq - NM_001242806
RefSeq - NM_001242807
RefSeq - NM_001242808
RefSeq - NM_001242810
RefSeq - NM_001726
RefSeq - NM_207189
RefSeq - XM_006710853
RefSeq - XM_006710854
RefSeq - XM_006710855
RefSeq - XM_006710856
RefSeq - XM_006710857
RefSeq - XM_011542032
RefSeq - XM_011542033
RefSeq - XM_011542034
RefSeq - XM_011542035
RefSeq Peptide - NP_001229736
RefSeq Peptide - NP_001229737
RefSeq Peptide - NP_001229739
RefSeq Peptide - NP_001717
RefSeq Peptide - NP_997072
RefSeq Peptide - NP_001229735
RefSeq Peptide - NP_001229734
swissprot - C9J1F7
swissprot - F8VZ63
swissprot - F8W0H2
swissprot - Q58F21
swissprot - C9J0Z0
swissprot - C9JQ27
swissprot - C9JMP1
swissprot - C9JLZ2
swissprot - C9JJU3
swissprot - C9JDL5
swissprot - C9JD82
Ensembl - ENSG00000137948
  
Related genetic diseases (OMIM): 617644 - ?Spermatogenic failure 21, 617644
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brdtENSDARG00000102802Danio rerio
 BRDTENSGALG00000006031Gallus gallus
 BrdtENSMUSG00000029279Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRD4 / O60885 / bromodomain containing 4ENSG0000014186742
BRD2 / P25440 / bromodomain containing 2ENSG0000020425639
BRD3 / Q15059 / bromodomain containing 3ENSG0000016992538
CREBBP / Q92793 / CREB binding proteinENSG0000000533920
EP300 / Q09472 / E1A binding protein p300ENSG0000010039318
BAZ2A / Q9UIF9 / bromodomain adjacent to zinc finger domain 2AENSG0000007610813
BAZ2B / Q9UIF8 / bromodomain adjacent to zinc finger domain 2BENSG0000012363613
BAZ1A / Q9NRL2 / bromodomain adjacent to zinc finger domain 1AENSG0000019860411
BAZ1B / Q9UIG0 / bromodomain adjacent to zinc finger domain 1BENSG0000000995410


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR018359  Bromodomain, conserved site
 IPR027353  NET domain
 IPR031354  Bromodomain protein 4, C-terminal
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001207 histone displacement IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007140 male meiotic nuclear division IEA
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0007283 spermatogenesis ISS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043484 regulation of RNA splicing IEA
 biological_processGO:0051039 positive regulation of transcription involved in meiotic cell cycle IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005634 nucleus ISS
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042393 histone binding IEA
 molecular_functionGO:0070577 lysine-acetylated histone binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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