ENSG00000204256


Homo sapiens

Features
Gene ID: ENSG00000204256
  
Biological name :BRD2
  
Synonyms : BRD2 / bromodomain containing 2 / P25440
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.32
Gene start: 32968660
Gene end: 32981505
  
Corresponding Affymetrix probe sets: 208685_x_at (Human Genome U133 Plus 2.0 Array)   208686_s_at (Human Genome U133 Plus 2.0 Array)   214911_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436322
Ensembl peptide - ENSP00000475288
Ensembl peptide - ENSP00000378702
Ensembl peptide - ENSP00000363964
Ensembl peptide - ENSP00000363958
Ensembl peptide - ENSP00000433751
Ensembl peptide - ENSP00000464077
Ensembl peptide - ENSP00000475691
Ensembl peptide - ENSP00000409145
Ensembl peptide - ENSP00000409613
Ensembl peptide - ENSP00000411195
Ensembl peptide - ENSP00000431514
NCBI entrez gene - 6046     See in Manteia.
OMIM - 601540
RefSeq - NM_001199456
RefSeq - NM_005104
RefSeq - NM_001113182
RefSeq - NM_001199455
RefSeq - NM_001291986
RefSeq Peptide - NP_001186384
RefSeq Peptide - NP_001106653
RefSeq Peptide - NP_005095
RefSeq Peptide - NP_001278915
RefSeq Peptide - NP_001186385
swissprot - X5CF57
swissprot - A0A024RCR5
swissprot - E9PIQ3
swissprot - E9PKQ9
swissprot - H0Y6K2
swissprot - H0Y799
swissprot - H0YDJ7
swissprot - J3QR72
swissprot - P25440
swissprot - U3KPW0
swissprot - U3KQA6
Ensembl - ENSG00000204256
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brd2aENSDARG00000022280Danio rerio
 BRD2ENSGALG00000000156Gallus gallus
 Brd2ENSMUSG00000024335Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BRD3 / Q15059 / bromodomain containing 3ENSG0000016992556
BRD4 / O60885 / bromodomain containing 4ENSG0000014186750
BRDT / Q58F21 / bromodomain testis associatedENSG0000013794844
CREBBP / Q92793 / CREB binding proteinENSG0000000533923
EP300 / Q09472 / E1A binding protein p300ENSG0000010039322
BAZ2B / Q9UIF8 / bromodomain adjacent to zinc finger domain 2BENSG0000012363616
BAZ2A / Q9UIF9 / bromodomain adjacent to zinc finger domain 2AENSG0000007610813
BAZ1A / Q9NRL2 / bromodomain adjacent to zinc finger domain 1AENSG0000019860412
BAZ1B / Q9UIG0 / bromodomain adjacent to zinc finger domain 1BENSG0000000995410


Protein motifs (from Interpro)
Interpro ID Name
 IPR001487  Bromodomain
 IPR018359  Bromodomain, conserved site
 IPR027353  NET domain
 IPR036427  Bromodomain-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006334 nucleosome assembly IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007283 spermatogenesis TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0070577 lysine-acetylated histone binding IDA


Pathways (from Reactome)
Pathway description
RUNX3 regulates p14-ARF


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000110092 CCND1 / P24385 / cyclin D1  / complex / reaction
 ENSG00000100393 EP300 / Q09472 / E1A binding protein p300  / reaction / complex
 ENSG00000067955 CBFB / Q13951 / core-binding factor beta subunit  / reaction / complex
 ENSG00000020633 RUNX3 / Q13761 / runt related transcription factor 3  / complex / reaction
 ENSG00000068024 HDAC4 / P56524 / histone deacetylase 4  / complex / reaction
 ENSG00000204256 BRD2 / P25440 / bromodomain containing 2  / complex






 

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